Results 121 to 130 of about 395,666 (242)

Terazosin Attenuates Neuronal Pyroptosis by Regulating the Mitochondrial ROS/NLRP3 Inflammasome Axis Through Mitophagy in Cerebral Ischemia–Reperfusion Injury

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Cerebral ischemia–reperfusion injury (CI/RI) is a major cause of secondary neuronal damage following ischemic stroke. This study investigated whether terazosin (TZ) exerts neuroprotective effects by regulating mitophagy and the reactive oxygen species (ROS)/NOD‐like receptor protein 3 (NLRP3) inflammasome axis.
Wei Wang, Xin‐Yue Han, Li‐An Huang, Yu‐Sheng Zhang, Heng Meng, An‐Ding Xu   +5 more
wiley   +1 more source

Implementation of a quality improvement initiative in Belgian diabetic foot clinics : feasibility and initial results

, 2014
: Background This article aims to describe the implementation and initial results of an audit-feedback quality improvement initiative in Belgian diabetic foot clinics.
Van Acker, Kristien, Lauwers, Patrick, Beele, Hilde, Doggen, Kris, et al.   +4 more
core  

Scalable Large Field‐of‐view 3D Photoacoustic Ultrasound Imaging With Digital Multiplexing for Human Extremities

Laser &Photonics Reviews, EarlyView.
A digitally multiplexed, large‐aperture photoacoustic and ultrasound imaging architecture is presented to overcome the fundamental limited‐view artifact inherent in conventional arrays. By significantly broadening the structural detection coverage, this scalable platform enables high‐fidelity 3D visualization of human extremities within a single ...
Sinyoung Park, Minsik Sung, Hyunhee Kim, Kijong Lee, Joongho Ahn, Eun‐Yeong Park, Sungsik Park, Hyung Ham Kim, Chulhong Kim   +8 more
wiley   +1 more source

Immunomodulatory, Antibacterial, Antioxidative and EGF‐Delivering Hydrogel Remodels Wound Microenvironment for Infected Diabetic Wound Healing

National Materials, EarlyView.
In this study, we engineered an antibacterial, antioxidative and epidermal grow factor‐encapsulated multifunctional hydrogel for the repair of chronic and refractory wounds. The hydrogel markedly promoted wound healing in rat models of diabetic foot ulcers and infected wounds by modulating wound microenvironment.
Zheng Zou, Yang Gao, Desheng Qi, Zhen Zhang, Chaoliang He, Xuesi Chen   +5 more
wiley   +1 more source

Treatment of Recalcitrant Diabetic Ulcers with Trichloroacetic Acid and Fibroblasts; Case Report

مجله دانشکده پزشکی اصفهان, 2015
Background: Foot ulcer, with a prevalence of 15% in general population, is one of the main complications in patients with diabetes. So far, different therapeutic methods have been provided for the treatment of foot ulcers.
Mohammad Ali Nilforoushzadeh, Fariba Jaffary, Mansour Siavash, Asieh Heidari, Nazli Ansari, Amir Hossein Siadat   +5 more
doaj  

Feasibility and Exploratory Outcomes of Foot‐Ankle and Walking Exercises for Diabetic Neuropathy, Stress, and Quality of Life: A Pilot Randomized Controlled Trial

Research in Nursing &Health, EarlyView.
ABSTRACT Foot–ankle and walking exercises have been proposed as potential strategies for managing symptoms in people with diabetic peripheral neuropathy (DPN), yet evidence from primary care remains limited. This pilot study assessed the feasibility and acceptability of these interventions and explored preliminary outcome patterns in DPN, stress, and ...
Siti Fadlilah, Wahyu Rochdiat Murdhiono, Ariyanto Nugroho, Yohanes Andy Rias, Shih Hsin Hsiao, Kai Ling Lee, Po Hao Feng, Hsiu Ting Tsai   +7 more
wiley   +1 more source

Congenital Intraoral Synechiae: A Scoping Review of Airway, Feeding, and Surgical Management

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To map the existing literature on congenital intraoral synechiae and summarize reported anatomic patterns, clinical presentation, associated anomalies/syndromes, and outcomes to inform standardized diagnostic and therapeutic approaches. Data Sources PubMed, CINAHL, Embase, Web of Science, and Google Scholar were searched from January
Jason Bernier, Mathieu Bergeron
wiley   +1 more source

Enterovirus infections in children

Pediatric Investigation, EarlyView.
Enteroviruses (EVs) are major pathogens causing a wide spectrum of diseases in children worldwide. This review summarizes the epidemiology, virology, viral replication, and virus‐host interactions of EVs. It also highlights current advances in clinical diagnosis, antiviral therapies, and vaccine development, providing insights into future strategies ...
Xiangpeng Chen, Lingyun Guo, Xiaobo Lei, Linqing Zhao, Mingyan Hei, Jun Shen, Ju Yin, Fei Li, Jikui Deng, Gang Liu, Yong Zhang, Zhengde Xie   +11 more
wiley   +1 more source

WTAP-mediated m6A RNA methylation promotes diabetic foot ulcer healing under negative pressure wound therapy. [PDF]

J Diabetes Investig
NPWT significantly increases the suppressed WTAP and m6A levels in DFU patients, correlating directly with better 4‐week healing outcomes. In vitro, negative pressure reverses high‐glucose‐induced WTAP downregulation, restoring the cell proliferation and migration necessary for wound repair.
Li Y, Chen W, Lu J, Lin X, Tang Y, Li J, Chen M.   +6 more
europepmc   +2 more sources

Characteristics, properties and limitations of per‐ or polyfluoroalkyl substances (PFASs) and fluoropolymers

Polymer International, EarlyView.
An overview and categorization of man‐made per‐ or polyfluoroalkyl substances (PFASs) including low‐molar‐mass and high‐molar‐mass fluorochemicals, and their international regulations is presented. Though certain PFASs are toxic, bioaccumulative and cross the human cellular membranes, others, such as fluoropolymers, are safe, reliable and involved in ...
Bruno Améduri
wiley   +1 more source