Results 21 to 30 of about 20,230 (282)

Recapitulation of pro-inflammatory signature of monocytes with ACVR1A mutation using FOP patient-derived iPSCs

Orphanet Journal of Rare Diseases, 2022
Background Fibrodysplasia ossificans progressiva (FOP) is a rare genetic disease characterized by progressive heterotopic ossification (HO) in soft tissues due to a heterozygous mutation of the ACVR1A gene (FOP-ACVR1A), which erroneously transduces the ...
Hirotsugu Maekawa, Yonghui Jin, Megumi Nishio, Shunsuke Kawai, Sanae Nagata, Takeshi Kamakura, Hiroyuki Yoshitomi, Akira Niwa, Megumu K. Saito, Shuichi Matsuda, Junya Toguchida   +10 more
doaj   +1 more source

International experience of FOP labeling for children's food and its enlightenment to China [PDF]

, 2023
Among the 10 front of package （FOP） labels for kid-friendly foods worldwide, Nutri-score labeling, health star rating system and especially warning labels could significantly guide children and their parents to reduce unhealthy food consumption. In fact,
HAN Jun-hua, YANG Yue-xin, HUANG Ze-ying, Yue-xin, YANG, Ze-ying, HUANG, Jun-hua, HAN   +5 more
core   +1 more source

Rapid Progression of Heterotopic Ossification in Severe Variant of Fibrodysplasia Ossificans Progressiva with p.Arg258Gly in ACVR1: A Case Report and Review of Clinical Phenotypes

Case Reports in Genetics, 2022
Fibrodysplasia ossificans progressiva (FOP) is a rare skeletal disorder characterized by congenital malformation of the great toes and progressive heterotopic ossification.
Kosei Hasegawa, Hiroyuki Tanaka, Natsuko Futagawa, Hiroyuki Miyahara, Hirokazu Tsukahara   +4 more
doaj   +1 more source

Effect of front-of-package labels on consumer product evaluation and preferences

Current Research in Food Science, 2022
Front-of-Package (FOP) labels highlight important nutrients and help consumers make informed decisions about food purchases. In this study, we investigated consumer comprehension, opinion, and preference associated with two different formats of FOP ...
Carlyn Oswald, Koushik Adhikari, Anand Mohan   +2 more
doaj   +1 more source

Myc-FOP-FGFR1 localizes to centriolar satellites.

, 2013
(A) Schematic of domain structure of FOP, FGFR1, and the FOP-FGFR1 fusion showing FOP LisH domain, FGFR1 kinase domains, and the translocation breakpoint.
Joanna Y. Lee (388303), Tim Stearns (106556)   +1 more
core   +1 more source

Classic and atypical fibrodysplasia ossificans progressiva (FOP) phenotypes are caused by mutations in the bone morphogenetic protein (BMP) type I receptor ACVR1 [PDF]

, 2008
Fibrodysplasia ossificans progressiva (FOP) is an autosomal dominant human disorder of bone formation that causes developmental skeletal defects and extensive debilitating bone formation within soft connective tissues (heterotopic ossification) during ...
Reardon, W., Stephen J. Forman, Stefan Mundlos, Bernhard Köster, Glaser, D.L., Fastnacht-Urban, E., Michael Zasloff, Connor, J.M., Seemann, P., Zasloff, M., Groppe, J., Elisabeth Fastnacht-Urban, William Reardon, Carroll, L., Frederick S. Kaplan, Gillessen-Kaesbach, G., Julie Hoover-Fong, Kaplan, F.S., Delai, P., Petra Seemann, Morhart, R., Mundlos, S., Koster, B., Zaidi, S.A., Richard M. Pauli, J. Michael Connor, Eileen M. Shore, Hoover-Fong, J., Pauli, R.M., Shore, E.M., Liam Carroll, Meiqi Xu, Rolf Morhart, Forman, S.J., Patricia Delai, Syed-Adeel Zaidi, Gabriele Gillessen-Kaesbach, David L. Glaser, Xu, M., Jay Groppe, Carroll, Liam, Zaidi, Syed-Adeel, Köster, Bernhard, Morhart, Rolf, Gillessen-Kaesbach, Gabriele, Hoover-Fong, Julie, Kaplan, Frederick S., Seemann, Petra, Xu, Meiqi, Reardon, William, Zasloff, Michael, Connor, Michael, Shore, Eileen M., Delai, Patricia, Fastnacht-Urban, Elisabeth, Mundlos, Stefan, Pauli, Richard M., Glaser, David L., Groppe, Jay, Forman, Stephen J.   +59 more
core   +1 more source

Copycat FOP labels: Do participants perceive copied (authentic) labels on products with copycat labels?

, 2022
Producers use copycat front-of-package (FOP) food labels that imitate other FOP labels. In this online study, we test if participants mistake copycat labels for their copied, authentic counterparts when reviewing grocery products.
Sonja Perkovic, Martin Schoemann, Piet van de Mosselaar, Jacob Lund Orquin   +3 more
core   +1 more source

BCX9250 is a potent small-molecule inhibitor of Activin A Receptor Type 1 (ACVR1/ALK2) for fibrodysplasia ossificans progressiva. [PDF]

JBMR Plus
Fibrodysplasia ossificans progressiva (FOP) is an ultra-rare genetic disease of heterotopic ossification caused by mutations in the ALK2 protein, a BMP type I receptor of the TGF-β superfamily. These mutations in the ALK2 receptor alter receptor function,
Wang H, Toutounchi S, Pignolo RJ, Cheng X, Parker CD, Liu Q, Muppa S, Kellogg-Yelder D, Polach KJ, Kotian PL, Babu YS, Chen X.   +11 more
europepmc   +2 more sources

FOP-FGFR1^V74F/E97K mutant lacks centrosome localization but not kinase activity.

, 2014
(A) Schematic of fusion between FOP and FGFR1 resulting in the FOP-FGFR1 oncogenic fusion and subsequent point mutations to produce KD, FOP-FGFR1K259A, and centrosome localization mutant, FOP-FGFR1V74F/E97K.
Joanna Y. Lee (388303), Wan-Jen Hong (540855), Ravindra Majeti (540856), Tim Stearns (106556)   +3 more
core   +1 more source

‘It just doesn't feel right’ and other reasons why some people fear and avoid positive emotions

Acta Psychologica, 2023
The need to further our understanding of positive affect dysregulation in depression has been widely acknowledged. Two related relevant concepts in this realm, are Avoidance Of Positivity (AOP; referring to avoidance behaviour towards positivity) and ...
Liesbeth Bogaert, Barnaby D. Dunn, Marta Walentynowicz, Filip Raes   +3 more
doaj   +1 more source