Results 41 to 50 of about 20,230 (282)

Copycat FOP labels: Mechanism

, 2023
This is a follow-up study to https://osf.io/ym8pg, in which we intend to test the mechanism behind the discovered effect. We assume that the color of the copycat FOP labels has the largest effect and hence manipulate the color of the copycat label and ...
Sonja Perkovic, Martin Schoemann, Piet van de Mosselaar, Jacob Lund Orquin   +3 more
core   +1 more source

Systematic Cardiac Phenotyping of Patients With Copy Number Variants in the 15q11.2 Breakpoint 1 to Breakpoint 2 Region: A Retrospective Cohort Study From Nine Pediatric Cardiac Centers

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Microdeletions impacting 15q11.2 breakpoint (BP) 1 to BP2, adjacent to the Prader–Willi critical region, have previously described neuropsychiatric associations, with potential low penetrance presentations of congenital heart disease (CHD) also identified.
Morgan B. Wright, Maria B. Padua, Lindsey R. Helvaty, Kim L. McBride, Gabrielle Geddes, Vidu Garg, Seema R. Lalani, Stephanie Burns Wechsler, Jennelle C. Hodge, Benjamin J. Landis, Stephanie M. Ware   +10 more
wiley   +1 more source

Fibrodysplasia Ossificans Progressiva: What Have We Achieved and Where Are We Now? Follow-up to the 2015 Lorentz Workshop

Frontiers in Endocrinology, 2021
Fibrodysplasia ossificans progressiva (FOP) is an ultra-rare progressive genetic disease effecting one in a million individuals. During their life, patients with FOP progressively develop bone in the soft tissues resulting in increasing immobility and ...
Ruben D. de Ruiter, Bernard J. Smilde, Gerard Pals, Nathalie Bravenboer, Petra Knaus, Ton Schoenmaker, Esmée Botman, Gonzalo Sánchez-Duffhues, Maurizio Pacifici, Robert J. Pignolo, Eileen M. Shore, Marjolein van Egmond, Hans Van Oosterwyck, Hans Van Oosterwyck, Frederick S. Kaplan, Edward C. Hsiao, Paul B. Yu, Renata Bocciardi, Carmen Laura De Cunto, Patricia Longo Ribeiro Delai, Teun J. de Vries, Susanne Hilderbrandt, Susanne Hilderbrandt, Richard T. Jaspers, Richard Keen, Peter Koolwijk, Rolf Morhart, Jan C. Netelenbos, Thomas Rustemeyer, Christiaan Scott, Clemens Stockklausner, Peter ten Dijke, James Triffit, Francesc Ventura, Roberto Ravazzolo, Dimitra Micha, Elisabeth M. W. Eekhoff   +36 more
doaj   +1 more source

Evaluating discrepancies between high‐yield neuroscience conditions in preclerkship medical education and national clinical incidence

Anatomical Sciences Education, EarlyView.
Abstract Medical education must balance foundational science with clinical relevance. Increasing emphasis on standardized assessments has led to prioritization of “high‐yield” conditions—those most likely to be assessed. Subsequently, educators and students often prioritize these conditions.
Kathryn Veazey, Oheneba Boadum
wiley   +1 more source

Serum osteocalcin level is associated with the mortality in Chinese patients with Fibrodysplasia ossificans progressiva aged ≤18 years at diagnosis

BMC Musculoskeletal Disorders, 2020
Background Fibrodysplasia ossificans progressiva (FOP) is an ultra-rare genetic disorder characterized by extraskeletal heterotopic ossification. It is well recognized that FOP can lead to a devastating condition of disability.
Dunmin She, Ran Li, Ping Fang, Guannan Zong, Ying Xue, Keqin Zhang   +5 more
doaj   +1 more source

FOP depletion reduces frequency of ciliated cells.

, 2013
(A) Western blot analysis of lysates from RPE-1 cells transfected with nontargeting (control) or FOP siRNA #1, #2, or #3. Relative FOP protein levels are calculated as the ratio of FOP/GAPDH for each lane, normalizing the control level to 1.
Joanna Y. Lee (388303), Tim Stearns (106556)   +1 more
core   +1 more source

Principal Component‐Based Classification of Blazar Candidates of Uncertain Type in the 4FGL/LAT

Astronomische Nachrichten, EarlyView.
ABSTRACT We adopted principal component analysis (PCA), linear discriminant analysis (LDA), and support vector machines (SVM), to study classification for a sample of 2708 Fermi blazars: 1142 BL Lac objects (BLLs), 759 flat spectrum radio quasars (FSRQs), and 807 blazar candidates of uncertain type (BCUs).
Wen‐Xin Yang, Guo‐Hai Chen, Jing‐Tian Zhu, Hong‐Guang Wang, Denis Bastieri, Xu‐Hong Ye, Jing‐Chao Liang, De‐Xiang Wu, Jiang‐He Yang, Anton A. Strigachev, Rumen S. Bachev, Jun‐Jie Feng, Yi Liu, Jun‐Hui Fan   +13 more
wiley   +1 more source

Eritema multiforme mayor desencadenado por antimicrobianos

Revista Cubana de Estomatología, 2010
El eritema multiforme, aparece como una enfermedad sistémica con la participación de la piel y las membranas mucosas en relación con varios factores como las infecciones bacterianas o virales, y en particular la administración de drogas, analgésicos y ...
Ronaldo de Carvalho Raimundo, Thiago de Santana Santos, José Paulo da Silva Filho, Daniela Guimarães de Melo Albert, Emanuel Dias de Oliveira e Silva, Ana Cláudia Amorim Gomes   +5 more
doaj  

Recursos educacionais no ensino da tomografia computadorizada de feixe cônico: um relato de experiência na graduação

Cadernos Cajuína
O ensino tradicional na Educação Superior carece de inovação instrucional, um desafio acentuado na Odontologia pela escassez de metodologias ativas voltadas à interpretação espacial tridimensional de imagens.
Luís Felipe Gomes Veloso, Maria Júlia Alves dos Anjos, Alycia Gabriella Delmas de Araújo, Adriana da Costa Ribeiro Yamada, Luciane Farias de Araújo, Híttalo Carlos Rodrigues de Almeida   +5 more
doaj   +1 more source

Clinical relevance of pharmacogenomic information for improving prescribing practices in acutely admitted older medical patients

British Journal of Clinical Pharmacology, EarlyView.
Aims Safe prescribing and effective medication review during acute hospitalization depends on accurate information about liver and kidney function because these organs are responsible for the elimination of most medications. While estimates for kidney function are widely used, comparable markers of hepatic drug‐metabolizing capacity are not routinely ...
Louise Westberg Strejby Christensen, Anne Kirstine Boas, Emilie Clausen, Nicoline Elers Koch, Anne Byriel Walls, Lotte Stig Nørgaard, Michael Asger Andersen, Anissa Aharaz, Rikke Lundsgaard Nielsen, Olivia Bornæs, Juliette Tavenier, Baker Nawfal Jawad, Helle Gybel Juul‐Larsen, Esben Iversen, Ove Andersen, Lona Louring Christrup, Kim Peder Dalhoff, Morten Baltzer Houlind   +17 more
wiley   +1 more source