Results 41 to 50 of about 76,929 (243)

Effects of Renal and Hepatic Impairment on the Pharmacokinetics of Zilurgisertib

British Journal of Clinical Pharmacology, EarlyView.
Aim Small‐molecule activin receptor‐like kinase‐2 inhibitor zilurgisertib (INCB000928) is under investigation in a pivotal trial for the treatment of fibrodysplasia ossificans progressiva (FOP), an ultrarare genetic condition. This analysis assessed effects of renal and hepatic impairment on zilurgisertib pharmacokinetics.
Yan‐ou Yang, Yunlan Fang, Phillip Wang, Xiang Liu, Jay Getsy, Kevin Rockich   +5 more
wiley   +1 more source

The effect of fear of progression on quality of life among breast cancer patients: the mediating role of social support

Health and Quality of Life Outcomes, 2021
Background Women with breast cancer are prone to have mental stress and be stimulated by the fear of progression (FOP), then giving rise to a lower quality of life (QOL).
Yue Ban, Mengyao Li, Mingli Yu, Hui Wu
doaj   +1 more source

Reação de genótipos provenientes de uma população de mapeamento para resistência a murcha de Curtobacterium flaccumfaciens pv. flaccumfaciens e Fusarium oxysporum f. sp. phaseoli em feijoeiro-comum. [PDF]

, 2014
Avaliou-se a ocorrência de murcha de curtobacterium (Cff) e murcha de fusarium (Fop) em plantas de feijoeiro provenientes de retrocruzamentos de duas cultivares, Ouro Branco e CNFP 10132, nas dependências da Embrapa Arroz e Feijão em Santo Antonio de ...
CORTÊS, M. V. de C. B., COSTA, J. G. C. da, FARIA, L. C. de, LIMA, S. C. D. V., MELO, L. C., OLIVEIRA, M. I. S., PAPA, G. G., PEREIRA, H. S., SOUZA, T. L. P. O. de, THEODORO, G. de F., WENDLAND, A.   +10 more
core  

A structural systematic study of three isomers of difluoro-N-(4-pyridyl)benzamide [PDF]

, 2008
The isomers 2,3-, (I), 2,4-, (II), and 2,5-difluoro-N-(4-pyridyl)benzamide, (III), all with formula C₁₂H₈F₂N₂O, all exhibit intramolecular C-H...O=C and N-H...F contacts [both with S(6) motifs].
Anderson, Frankie P., Gallagher, John F., Lough, Alan J., McMahon, Joyce   +3 more
core   +1 more source

Academic misconduct appeal services in China: Platform logics, self‐platformization and implications for integrity education

British Educational Research Journal, EarlyView.
Abstract Academic misconduct appeal services have quietly emerged within China's education marketplace, with commercial agencies promoting themselves on social media to assist international students facing misconduct hearings. While existing research on academic integrity has emphasized prevention and detection, far less attention has been paid to what
Gengyan Tang, Sarah Elaine Eaton, Wei Cai   +2 more
wiley   +1 more source

Fear of progression among postoperative patients with newly diagnosed lung cancer: a cross-sectional survey in China

BMC Psychology, 2023
Background More lung cancer cases are becoming diagnosed earlier in recent years. The diagnosis is often accompanied by fear of progression (FoP). There is a clear research gap in the existing literature on FoP and the most frequent concerns in newly ...
Ruiyun Chen, Hui Yang, Hongmei Zhang, Jingru Chen, Saisai Liu, Li Wei   +5 more
doaj   +1 more source

Embryonic cerebrospinal fluid pressure in fetal mice in utero: External factors pressurize the intraventricular space

Developmental Dynamics, EarlyView.
Abstract Background Previous experiments inducing leakage of embryonic cerebrospinal fluid (CSF) suggest the necessity of intraventricular CSF pressure (PCSF) for brain morphogenesis. Nevertheless, how embryonic PCSF occurs is unclear, especially in utero. Results Using a Landis water manometer, we measured PCSF in fetal mice isolated from the amniotic
Koichiro Tsujikawa, Reina Muramatsu, Takaki Miyata   +2 more
wiley   +1 more source

Nutrient intakes and top food categories contributing to intakes of energy and nutrients-of-concern consumed by Canadian adults that would require a 'high-in' front-of-pack symbol according to Canadian labelling regulations.

PLoS ONE, 2023
Canada recently mandated front-of-pack (FOP) labelling regulations, where foods meeting and/or exceeding recommended thresholds for nutrients-of-concern (i.e., saturated fat, sodium, and sugars) must display a 'high-in' FOP nutrition symbol.
Jennifer J Lee, Mavra Ahmed, Alena Praneet Ng, Christine Mulligan, Nadia Flexner, Mary R L'Abbé   +5 more
doaj   +1 more source

Mediation Effects of Coping Styles on Fear of Progression and Reproductive Concerns in Breast Cancer Patients of Reproductive Age

Asian Nursing Research, 2023
Summary: Purpose: This study aimed to investigate reproductive concerns among breast cancer patients of reproductive age, analyze the influencing factors, explore the relationship between coping styles, fear of progression (FOP), and reproductive ...
Cuiting Liu, Cuiping Liu, Huiting Gao, Xuefen Yu, Chunying Chen, Hangying Lin, Lijuan Qiu, Liangying Chen, Hongmei Tian   +8 more
doaj   +1 more source

The relationship between cellular protein content and selenium accumulation in freshwater microalgae

Integrated Environmental Assessment and Management, EarlyView.
Abstract Variability in the bioconcentration of selenium (Se) by primary producers at the base of the food web results in uncertainty in predictions of bioaccumulation and ecological risk to higher trophic level organisms. Water chemistry, speciation of Se, and periphyton community composition have all been suggested as factors that contribute to ...
Courtney Bogstie, Melanie Gallant, James R. Elphick, Christopher Kennedy   +3 more
wiley   +1 more source