Results 71 to 80 of about 2,671,986 (314)

The FoldX web server: an online force field

Nucleic Acids Res., 2005
FoldX is an empirical force field that was developed for the rapid evaluation of the effect of mutations on the stability, folding and dynamics of proteins and nucleic acids. The core functionality of FoldX, namely the calculation of the free energy of a
J. Schymkowitz, J. Ferkinghoff-Borg, F. Stricher, R. Nys, F. Rousseau, L. Serrano   +5 more
semanticscholar   +1 more source

Are Force Enhancement after Stretch and Muscle Fatigue Due to Effects of Elevated Inorganic Phosphate and Low Calcium on Cross Bridge Kinetics? [PDF]

, 2020
Hans Degens, David A. Jones
openalex   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Inadmissible Forcing

Advances in Mathematics, 1987
The notion of a partial recursive function has been generalized by Normann and Moschovakis so that arbitrary sets are allowed as arguments. The authors use a forcing technique over transitive, recursively closed sets to prove the following: if L(\(\kappa)\) is countable, recursively closed, non \(\Sigma_ 1\)-admissible and the greatest cardinal of L(\(\
Sacks, G.E, Slaman, T.A
openaire   +1 more source

Features of Electrostatic Fields and Their Force Action When Using Micro- and Nanosized Inter-Electrode Gaps [PDF]

, 2020
Н. С. Пщелко, E. G. Vodkaĭlo
openalex   +1 more source

Characteristics of myocardial work during exercise stress echocardiography in healthy adults

Frontiers in Cardiovascular Medicine
BackgroundNon-invasive myocardial work (MW) is a more precise parameter for evaluating left ventricular (LV) systolic function. However, studies examining sex-based differences in MW during exercise stress echocardiography (SE) in healthy individuals are
Liwei Huang, Liwei Huang, Luwei Ye, Luwei Ye, Hongmei Zhang, Hongmei Zhang, Qingfeng Zhang, Qingfeng Zhang, Geqi Ding, Geqi Ding, Chunmei Li, Chunmei Li, Yan Deng, Yan Deng, Lixue Yin, Lixue Yin, Yi Wang, Yi Wang   +17 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

In Vitro Flexural Testing of Clear Aligner Materials: A Scoping Review of Methods, Results, and Clinical Relevance

Applied Sciences
Background: Clear aligner therapy (CAT) has become increasingly popular for treating mild to moderate malocclusions. However, discrepancies between predicted and achieved tooth movement remain a concern, partly due to the limited understanding of aligner
Gavin Nugent, Alvaro Munoz, Chris Louca, Alessandro Vichi   +3 more
doaj   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Chemically characterizing the cortical cell nano‐structure of human hair using atomic force microscopy integrated with infrared spectroscopy (AFM‐IR)

, 2021
Alexander P. Fellows, Michael T. L. Casford, Paul B. Davies   +2 more
openalex   +1 more source