Results 71 to 80 of about 7,852,123 (299)

Simultaneous current, force and dissipation measurements on the Si(111) 7×7 surface with an optimized qPlus AFM/STM technique

Beilstein Journal of Nanotechnology, 2012
We present the results of simultaneous scanning-tunneling and frequency-modulated dynamic atomic force microscopy measurements with a qPlus setup. The qPlus sensor is a purely electrical sensor based on a quartz tuning fork. If both the tunneling current
Zsolt Majzik, Martin Setvín, Andreas Bettac, Albrecht Feltz, Vladimír Cháb, Pavel Jelínek   +5 more
doaj   +1 more source

Force-gradient-induced mechanical dissipation of quartz tuning fork force sensors used in atomic force microscopy

, 2011
We have studied the dynamics of quartz tuning fork resonators used in atomic force microscopy taking into account mechanical energy dissipation through the attachment of the tuning fork base.
A. Castellanos-Gomez, Albers, Castellanos-Gomez, Castellanos-Gomez, Cleveland, Edwards, G. Rubio-Bollinger, Giessibl, Giessibl, Grober, Ihn, Karrai, le Sueur, N. Agraït, Naber, Ng, Oral, Rensen, Rubio-Bollinger, Seo, Shelimov, Smit, Valkering   +22 more
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Force-feeding Black Holes

, 2012
We propose that the growth of supermassive black holes is associated mainly with brief episodes of highly super-Eddington infall of gas ("hyperaccretion"). This gas is not swallowed in real time, but forms an envelope of matter around the black hole that
Begelman, Begelman, Ferrarese, Gebhardt, Gruzinov, Hopkins, Jaroszyński, King, Levine, Narayan, Paczyński, Quataert, Shakura, Shaviv, Sikora, Tremaine, Wise   +16 more
core   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Calculation of secondary electron trajectories in multistage depressed collectors for microwave amplifiers [PDF]

Computational procedures are reported for treating power losses due to secondary electrons in multistage depressed collectors (MDC) for traveling wave tubes (TWT) and other O-type electron tubes.
Force, Dale A.
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Commentary on the development of a new tool for embryologists to detect testicular sperm cells

Asian Journal of Andrology, 2021
Benoit Schubert, Andre Force
doaj   +1 more source