Albumin‐Bound STING Agonist Reprograms HSPCs to Antitumor Neutrophils Enhancing CD8+ T Cell Immunity
Advanced Science, EarlyView.This study demonstrates that an albumin‐bound STING agonist (Nano ZSA‐51D) reprograms HSPCs to produce antitumor neutrophils with enhanced MHC I–mediated CD8+ T cell activation, thereby sensitizing tumors to α‐PD1 therapy. These findings highlight a strategy to target early hematopoiesis for shaping neutrophil fate and potentiating cancer immunotherapy.
Jinsong Tao +11 more
wiley +1 more source
Bite Force Distribution and Occlusal Adjustment in Stainless Steel Crowns and BioFlx Crowns of Children Aged 4-8 Years. [PDF]
Int J Clin Pediatr DentSingh T +6 more
europepmc +1 more source
Lithiation‐Driven LiCrSe2 Shell Growth on Metallic CrSe2 Core Governs the Plateau–Slope Behavior
Advanced Science, EarlyView.Layered CrSe2 is investigated as a lithium‐ion battery cathode combining fast Li+ diffusion and structural reversibility. Calculations and experiments reveal a single topotactic intercalation process with a characteristic plateau–slope profile governed by lithiation‐induced conductivity changes. A core‐shell lithiation evolution underpins its high‐rate
Weihao Li +15 more
wiley +1 more source
How does agricultural insurance affect income inequality within farmers? Based on survey data from Shandong Province, China. [PDF]
PLoS OneShe Z, Sun L, Yuan Y, Chen S.
europepmc +1 more source
On the Ordering Mechanism of Cu+ in 2D van der Waals Multiferroic CuCrP2S6
Advanced Science, EarlyView.Temperature‐dependent X‐ray single‐crystal diffuse scattering measurements of CuCrP2S6 in the (H, K, 0) plane reveal the gradual emergence and strengthening of short‐range order upon cooling from 230 to 170 K. At intermediate temperatures, diffuse features become pronounced and eventually lock into sharp incommensurate satellite reflections, indicating
Jiasen Guo +5 more
wiley +1 more source
Comparison of plyometric training using differential learning versus nonlinear pedagogy on functional, biomechanical factors in athletes at high risk of A. C. L. injury: protocol for aparallel-group randomized controlled trial. [PDF]
TrialsHamoongard M +4 more
europepmc +1 more source
Peroxidase‐Mimicking Nanozymes for Rapid Detection of Infectious Diseases
Advanced Science, EarlyView.Peroxidase‐mimicking nanozymes (PMNs) have emerged as robust and versatile materials for rapid infectious disease diagnostics. This review highlights the rational design and controlled synthesis of PMNs, summarizes key biomarkers relevant to infectious diseases, examines their integration into diverse rapid detection platforms, and highlights ...
Shikuan Shao +5 more
wiley +1 more source
Position paper on the existing selection procedure in Germany for the degree program human medicine - interim evaluation after four years. Position paper of the student selection (ASA) in the DACH Association for Medical Education (GMA). [PDF]
GMS J Med EducMüller-Hilke B, Gehlhar K.
europepmc +1 more source
Fabrication of High‐Density Multimodal Neural Probes Based on Heterogeneously Integrated CMOS
Advanced Science, EarlyView.A chiplet‐based methodology democratizes active neural probe development on standard bulk CMOS services. This yields the first probe combining high‐density electrophysiology (416 electrodes) with calcium imaging (832 photodiodes) and complete on‐chip signal processing across 13 shanks.
Ju Hee Mun +10 more
wiley +1 more source
Angled manual traction and usual care for cervical radiculopathy: rationale and a protocol for a pilot randomized controlled trial (pAMTLER). [PDF]
Front Med (Lausanne)Liao S +7 more
europepmc +1 more source