Results 31 to 40 of about 69,169 (263)

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Adaptive Force Ratio Allocation for Multi-UAV Cooperative Multi-Target Encirclement

Drones
The size of an unmanned aerial vehicle (UAV) swarm and the capabilities of each individual in the swarm are critical determinants of mission effectiveness in multi-target encirclement. This paper proposes a framework for strategic force allocation during
Qiting Liu, Meixuan Li, Xianqiang Zhu
doaj   +1 more source

Optimal Orientation Planning and Control Deviation Estimation on FAST Cable-Driven Parallel Robot

Advances in Mechanical Engineering, 2014
The paper is devoted theoretically to the optimal orientation planning and control deviation estimation of FAST cable-driven parallel robot. Regarding the robot characteristics, the solutions are obtained from two constrained optimizations, both of which
Hui Li, Rui Yao
doaj   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

De novo synthesis of short‐chain aldehydes and hydrocarbons secreted by the brown marmorated stink bug Halyomorpha halys

FEBS Open Bio, EarlyView.
The brown marmorated stink bug, Halyomorpha halys, mainly secretes 4‐oxo‐(E)‐2‐hexenal, (E)‐2‐decenal, dodecane and tridecane, a mixture representative of that released by many heteropterans. We demonstrated that H. halys can synthesise these secretory components de novo using dietary glucose.
Haruna Fujimori, Koji Noge
wiley   +1 more source

Hierarchical Coordination Control of Distributed Drive Intelligent Vehicle Based on TSMPC and Tire Force Optimization Allocation

Algorithms
An intelligent vehicle hierarchical coordinated control strategy based on time delay state feedback model predictive control (TSMPC) and tire force optimization allocation is presented.
Junmin Li, Fei Wang, Wenguang Guo, Zhengyong Zhou, Shuaike Miao, Te Chen   +5 more
doaj   +1 more source

Intelligent Tutoring Systems for Adult Learning in STEM Disciplines

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Intelligent tutoring systems (ITS) are reshaping adult learning in STEM by providing adaptive, data‐driven instruction across classrooms, workplaces, and informal environments. In the context of ITS, this article compares generative AI, which creates personalized explanations and practice materials, with explainable AI, which focuses on ...
Jill Zarestky, Amanda R. Lager Gleason
wiley   +1 more source

Research on the Stability Control Strategy of Distributed Electric Vehicles Based on Cooperative Reconfiguration Allocation

World Electric Vehicle Journal, 2023
Aiming at the problem of body instability caused by actuator failure in a distributed electric vehicle drive system, a fault-tolerant control strategy of longitudinal and lateral force cooperative reconstruction with active steering control was proposed,
Jian Ou, Dehai Yan, Yong Zhang, Echuan Yang, Dong Huang   +4 more
doaj   +1 more source

Effects of Add‐On Icosapent Ethyl With Standard Treatment on Functional Outcomes and Inflammatory Biomarkers in Acute Ischemic Stroke: A Blinded Randomized Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand, Seyed Hossein Aghamiri, Saeed Mohmammad Soleymani, Shadiyeh Bararpoor Poshkohi, Samaneh Masoudi, Hadi Esmaily   +5 more
wiley   +1 more source

Vegetation C–N–P accumulation and allocation patterns at the community level in early restored plantations in the loess hilly-gully region

Forest Ecosystems, 2023
Accumulation of vegetation biomass is a crucial process for carbon fixation in the early stage of afforestation and a primary driving force for subsequent ecological functions. Accurately assessing the storage and allocation of elements in plantations is
Huifeng Wu, Baoan Hu, Ying Ma, Wenkai Shi, Xiaoqin Cheng, Fengfeng Kang, Hairong Han   +6 more
doaj   +1 more source