Results 121 to 130 of about 569,034 (301)

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Design of Low-frequency Impact Frequency Measuring Circuit with Resistance Strain Force Sensor

open access: yesGong-kuang zidonghua, 2012
In view of problems of high cost and inconvenient installation by use of piezoelectric force sensor and impact force sensor to measure impact frequency, a low-frequency impact frequency measuring circuit with resistance strain force sensor was designed ...
LIU Jian-zhao   +4 more
doaj  

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Improvement and application of variable-sensitivity force sensors using shape-memory polymer

open access: yesNihon Kikai Gakkai ronbunshu
This study presents a variable-sensitivity force sensor utilizing a shape-memory polymer (SMP) sheet embedded with an electric heating wire, whose stiffness fluctuates with temperature changes.
Taichi TANIGUCHI, Kazuto TAKASHIMA
doaj   +1 more source

Stress relaxation of the infusion tube with a pressure sensor

open access: yesMATEC Web of Conferences, 2018
We studied stress relaxation of the infusion tube with a pressure sensor using FEA method. The stress distribution in the tube, the contact pressure on the wall of the pressure sensor, the decay of the reaction force on the wall of the pressure sensor ...
Xie Aoru
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

The flight demonstration program and selection process [PDF]

open access: yes
The Orbital Refueling System (ORS); force torque sensor; Plasma Motor/Generator (PMG) proof of function; voice controlled system; infrared intercommunications; superfluid helium on orbit transfer; laser docking sensor; and the Small Expendable Deployment
Levin, G. M.
core   +1 more source

Compliant tactile sensor that delivers a force vector [PDF]

open access: yes, 2010
Tactile Sensor. The sensor includes a compliant convex surface disposed above a sensor array, the sensor array adapted to respond to deformation of the convex surface to generate a signal related to an applied force vector.
Torres-Jara, Eduardo
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

The MSFC space station/space operations mechanism test bed [PDF]

open access: yes
The Space Station/Space Operations Mechanism Test Bed consists of the following: a hydraulically driven, computer controlled Six Degree-of-Freedom Motion System (6DOF); a six degree-of-freedom force and moment sensor; remote driving stations with ...
Sutton, William G., Tobbe, Patrick A.
core   +1 more source

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