Results 131 to 140 of about 2,946,335 (301)
Development of a Closed-loop MEMS Capacitive Force Sensor
, 2009 This thesis describes a closed-loop microelectromechanical system (MEMS) based on lumped-parameter modeling. Analytical models are derived for electrostatic comb drive actuator (CDA) under force-controlled actuation, electrothermal actuator (ETA) under ...
Guan, Changhong
core
Current Directions in Biomedical EngineeringIntroduction: Insertion forces acting during cochlear implant surgery have been associated with intracochlear trauma and loss of residual hearing, but are almost imperceptible. To enable intraoperative insertion force measurement, our group developed the
Shrestha Subiran +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Fiber Optic Sensor of Axial Strain and Dynamic Transverse Force Based on Intensity Demodulation
SensorsThis paper presents a fiber-optic sensor with intensity demodulation for simultaneous measurement of dynamic transverse force and axial strain. The sensor uses a Sagnac loop filter with a polarization-maintaining photonic crystal fiber (PM-PCF) that is ...
Cezary Kaczmarek, Malgorzata Detka
doaj +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Development and characterisation of traceable force measurement for nanotechnology [PDF]
Traceable low force metrology should be an essential tool for nanotechnology. Traceable measurement of micro- and nanonewton forces would allow independent measurement and comparison on material properties, MEMS behaviour and nanodimensional ...
Jones, Christopher W.
core
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Design, Modeling, and Micromanipulation Experiments of A Novel 2-D Micro Force Sensor
, 2009 Because of the micro/nano manipulation’s complexity, the accurate feedback information of the micro interactive force acting on micro devices is quite important and necessary for micro/nano manipulation, especially the 2-D micro interactive force ...
Liu YY(刘意杨) +3 more
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A novel PVDF microforce/force rate sensor for practical applications in micromanipulation
, 2004 This paper presents our development of a novel force and force rate sensory system to advance applications in micromanipulation using an in situ polyvinylidene fluoride (PVDF) piezoelectric sensor.
Li, Wen J. +3 more
core +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source