Results 131 to 140 of about 149,652 (313)
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Design of Low-frequency Impact Frequency Measuring Circuit with Resistance Strain Force Sensor
Gong-kuang zidonghua, 2012 In view of problems of high cost and inconvenient installation by use of piezoelectric force sensor and impact force sensor to measure impact frequency, a low-frequency impact frequency measuring circuit with resistance strain force sensor was designed ...
LIU Jian-zhao +4 more
doaj
Impedance control of a robot needle with a fiber optic force sensor
, 2016 In this paper, an impedance control is proposed for a robotic needle with a fiber optic force sensor. The fiber optic force sensor is placed at the tip of the needle to directly measure the interaction force between needle and soft tissue, overcoming the
Xu WL(徐卫良) +5 more
core
RuleCaster: A Macroprogramming System for Sensor Networks [PDF]
, 2006 Progress in the development of small low-powered hardware, wireless networking, sensor technology and software services make it possible to build radically new kinds of applications. These sensor network applications are built on top of a large number of
Bischoff, Urs, Kortuem, Gerd
core
Mass and Force Sensing of an Adsorbate on a Beam Resonator Sensor
, 2015 The mass sensing superiority of a micro-/nano-mechanical resonator sensor over conventional mass spectrometry has been, or at least is being firmly established.
张吟 +2 more
core +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Improvement and application of variable-sensitivity force sensors using shape-memory polymer
Nihon Kikai Gakkai ronbunshuThis study presents a variable-sensitivity force sensor utilizing a shape-memory polymer (SMP) sheet embedded with an electric heating wire, whose stiffness fluctuates with temperature changes.
Taichi TANIGUCHI, Kazuto TAKASHIMA
doaj +1 more source
Characteristics of a 9mm triple-beam tuning fork resonant sensor
, 2007 This paper describes the design and testing of the first miniaturised metallic triple-beam tuning fork resonant sensors for use in force, pressure and torque measurement applications. The new devices with 9mm length vibrating tines have resulted in over
Jones, BE +3 more
core +1 more source
Molecular Oncology, EarlyView.Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source