Results 121 to 130 of about 149,652 (313)

Integrated flexible hinge sensor design approach for electromagnetic force compensation weight detector

open access: yesDiance yu yibiao
As the core component of the electromagnetic force compensation weight detector, the force measurement sensitivity of the integrated flexible hinge sensor directly determines the resolution of the electromagnetic force compensation weight detector to ...
LIU Xiaohu   +5 more
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

ForceBalanceSensorBasedonElectromagneticForceBalanceLeverStructure

open access: yes工程科学与技术, 2016
:Because of the nonlinearity of the elastic sensitive element and the signal noise ratio,the precision of the traditional force sensor can hardly be higher than 0.02%.A force sensor with electromagnetic force balance lever structure was introduced.The ...
王秋晓, 沈利坚, 蒋盼, 杨远才
doaj  

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

open access: yesMolecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou   +12 more
wiley   +1 more source

A contact force measure sensor based on resistance-array-type sensor

open access: yes, 2017
As an ideal candidate for biology information detection, flexible resistance-array-type sensors have attracted extensive attention. But owing to the Neighbor Disturbance in resistance array, the accuracy of the sensors has been limited greatly.
He K(贺凯)   +3 more
core  

Classification and Prediction for Accurate Sensor-Based Assembly to Moving Objects

open access: yes, 2010
Typical industrial assembly tasks require an accuracy that cannot be realized by only feedback control if a minimum speed is given by a conveyor. Feed-forward has proven to be advantageous, using predictions of the desired trajectory which will be ...
Hirzinger, Gerd   +5 more
core   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Design, Modeling, and Micromanipulation Experiments of A Novel 2-D Micro Force Sensor

open access: yes, 2009
Because of the micro/nano manipulation’s complexity, the accurate feedback information of the micro interactive force acting on micro devices is quite important and necessary for micro/nano manipulation, especially the 2-D micro interactive force ...
Liu YY(刘意杨)   +3 more
core  

Optomechanical damping of a microcantilever force sensor in liquid [PDF]

open access: yes, 2010
A new instrument, constant deflection atomic force microscopy (CD-AFM) constructed to perform force spectroscopy measurements without mechanical instabilities associated with the use of soft AFM cantilevers has been developed, tested and calibrated ...
Al Zahrani, Khalid Eidah
core  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

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