Results 151 to 160 of about 149,652 (313)

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Enhancements of MEMS design flow for Automotive and Optoelectronic applications

open access: yes, 2010
In the latest years we have been witnesses of a very rapidly and amazing grown of MicroElectroMechanical systems (MEMS) which nowadays represent the outstanding state-of-the art in a wide variety of applications from automotive to commercial, biomedical ...
MARCHETTI, ELEONORA
core  

An Enhanced Virtual Force Algorithm for Diverse k-Coverage Deployment of 3D Underwater Wireless Sensor Networks

open access: yes, 2019
The combination of Wireless Sensor Networks (WSNs) and edge computing not only enhances their capabilities, but also motivates a series of new applications.
Fan He   +5 more
core   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

Fiber Optic Sensor of Axial Strain and Dynamic Transverse Force Based on Intensity Demodulation

open access: yesSensors
This paper presents a fiber-optic sensor with intensity demodulation for simultaneous measurement of dynamic transverse force and axial strain. The sensor uses a Sagnac loop filter with a polarization-maintaining photonic crystal fiber (PM-PCF) that is ...
Cezary Kaczmarek, Malgorzata Detka
doaj   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

Development of a Closed-loop MEMS Capacitive Force Sensor

open access: yes, 2009
This thesis describes a closed-loop microelectromechanical system (MEMS) based on lumped-parameter modeling. Analytical models are derived for electrostatic comb drive actuator (CDA) under force-controlled actuation, electrothermal actuator (ETA) under ...
Guan, Changhong
core  

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Identification of parameters for a Stewart platform-based force/torque sensor

open access: yes, 2004
In this paper, the mechanical configuration and the principle of the measurement for a Stewart platform-based multi-component force/torque sensor is introduced. A novel calibration method for geometric parameters is presented, which is to connect a fixed
Fang LJ(房立金)   +4 more
core  

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

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