Results 261 to 270 of about 3,129,995 (305)

Dielectrophoresis force spectroscopy for colloidal clusters

ELECTROPHORESIS, 2012
Optical trapping‐based force spectroscopy was used to measure the frequency‐dependent DEP forces and DEP crossover frequencies of colloidal polymethyl methacrylate spheres and clusters. A single sphere or cluster, held by an optical tweezer, was positioned near the center of a pair of gold‐film electrodes where alternating current elecroosmosis flow ...
Park, H Park, Hyunjoo, Wei, MT Wei, Ming-Tzo, Ou-Yang, HD Ou-Yang, H. Daniel   +2 more
openaire   +3 more sources

Force spectroscopy with single bio-molecules

Current Opinion in Chemical Biology, 2000
For many biological molecules, force is an important functional and structural parameter. With the rapidly growing knowledge about the relation between structure, function, and force, single-molecule force spectroscopy has become a versatile analytical tool for the structural and functional investigation of single bio-molecules in their native ...
H, Clausen-Schaumann, M, Seitz, R, Krautbauer, H E, Gaub   +3 more
openaire   +2 more sources

Friction Force Spectroscopy

1996
Two-dimensional histogram technique is used to determine the loading dependence of friction. Multifunctional dependence F F i (F N )is observed, where the index i represents different materials or inequivalent sites. The data are found to be in agreement with simple power laws, corresponding to the single asperity regime with contact radii of 1–4nm (1 ...
E. Meyer, R. Lüthi, L. Howald, M. Bammerlin, M. Guggisberg, H.-J. Güntherodt, L. Scandella, J. Gobrecht, A. Schumacher, R. Prins   +9 more
openaire   +1 more source

Spectroscopy and atomic force microscopy of biomass

Ultramicroscopy, 2010
Scanning probe microscopy has emerged as a powerful approach to a broader understanding of the molecular architecture of cell walls, which may shed light on the challenge of efficient cellulosic ethanol production. We have obtained preliminary images of both Populus and switchgrass samples using atomic force microscopy (AFM).
L, Tetard, A, Passian, R H, Farahi, U C, Kalluri, B H, Davison, T, Thundat   +5 more
openaire   +2 more sources

Plastic Tip Arrays for Force Spectroscopy

Analytical Chemistry, 2004
The mechanical stability and viability of molecules investigated with the atomic force microscope (AFM) continue to be limiting factors in the duration of force spectroscopy measurements. In an effort to circumvent this problem, we have fabricated an all-plastic array of over 30 000 tips with dimensions similar to common AFM probes using silicon ...
Peter T, Lillehei, Mark A, Poggi, Brian J, Polk, J Anthony, Smith, Lawrence A, Bottomley   +4 more
openaire   +2 more sources

Small Amplitude Atomic Force Spectroscopy

2010
Over the years atomic force microscopy has developed from a pure imaging technique to a tool that can be employed for measuring quantitative tip–sample interaction forces. In this chapter we provide an overview of various techniques to extract quantitative tip–sample forces focusing on both amplitude modulation and frequency modulation atomic force ...
de Beer, Sissi, van den Ende, Henricus T.M., Ebeling, Daniel, Mugele, Friedrich Gunther   +3 more
openaire   +2 more sources

Nanopore Force Spectroscopy on DNA Duplexes

2009
Force spectroscopy can be applied using nanopores to study charged molecules such as nucleic acids. This technique can be used to study the binding energy of a DNA duplex by threading an anchored single-stranded DNA (ssDNA) probe molecule through a nanopore (having a diameter large enough to accommodate only a single strand) and allowing target DNA on ...
Nahid N, Jetha, Matthew, Wiggin, Andre, Marziali   +2 more
openaire   +2 more sources

Simulation in Force Spectroscopy

2008
Simulation has played an important role in the study of molecular-scale forces since the 1970s, almost from the time such forces could first be measured experimentally. Over the past three decades, as experimental probes have grown in sophistication and sensitivity, the scope and accuracy of computer modeling have developed in step.
openaire   +1 more source

SDynamic Force Spectroscopy with the Atomic Force Microscope

2008
By studying the effect of force on the dissociation kinetics of molecular interactions, hitherto hidden information about physics, chemistry, and biology is gained. Since the statement of the theory and the first demonstration of the experiment [2], we have seen developments in theory, experimental practice, and data analysis.
openaire   +1 more source

Correlation Force Spectroscopy

2015
The main advantage of correlation force spectroscopy (CFS) over atomic force microscopy (AFM) is that the thermal noise in the cross-correlation between two cantilevers (CFS design) is much smaller than the thermal noise in the autocorrelation of a single cantilever (AFM design). In this chapter, this is examined experimentally.
openaire   +1 more source