This study examines the association between the rs1042713 (Arg16Gly) polymorphism of the β2‐adrenergic receptor and the risk of severe eosinophilic asthma, as well as its influence on mepolizumab long‐term effectiveness and clinical remission. The Arg16 allele is associated with increased risk of severe disease and potentially diminished long‐term ...
Santi Nolasco +38 more
wiley +1 more source
What drives rescue bronchodilators overuse in asthma patients? Demographic features, low forced expiratory volume in 1 s and high sputum eosinophil counts. [PDF]
Louis F +6 more
europepmc +1 more source
The Nasal Microbiome and Associations With Environmental Exposures and Respiratory Health
This study evaluates the association of the nasal microbiome with air pollutants, meteorological conditions, and respiratory health in adolescents. Bacterial diversity is positively associated with hay fever and short‐term NO2 exposure, and negatively with temperature. A Moraxella‐dominated nasotype is linked to lower O3 exposure and higher temperature
Javier Perez‐Garcia +11 more
wiley +1 more source
Two forced expiratory volume in 1 s trajectories with distinct prognoses in pulmonary Langerhans cell histiocytosis. [PDF]
Benattia A +5 more
europepmc +1 more source
Prognostic marker for severe acute exacerbation of chronic obstructive pulmonary disease: analysis of diffusing capacity of the lung for carbon monoxide (DLCO) and forced expiratory volume in one second (FEV1). [PDF]
Choi J +8 more
europepmc +1 more source
The Concave Shape of the Forced Expiratory Flow-Volume Curve in 3 Seconds Is a Practical Surrogate of FEV 1 /FVC for the Diagnosis of Airway Limitation in Inadequate Spirometry [PDF]
Hao Li, Chunhong Liu, Yi Zhang, Wei Xiao
openalex +1 more source
Protective Role for Itaconate During Inhaled Allergen Challenge
Itaconate levels decrease in sputum following allergen inhalation in mild asthmatics, suggesting a dynamic metabolic response to airway challenge. Genetic deletion of Acod1 in mice did not alter airway inflammation or remodelling in response to chronic HDM exposure.
Gesa J. Albers +16 more
wiley +1 more source

