Results 41 to 50 of about 118,717 (344)
New Spirometry Indices for Detecting Mild Airflow Obstruction. [PDF]
The diagnosis of chronic obstructive pulmonary disease (COPD) relies on demonstration of airflow obstruction. Traditional spirometric indices miss a number of subjects with respiratory symptoms or structural lung disease on imaging.
Barjaktarevic, Igor+13 more
core +2 more sources
Changes in Forced Expiratory Volume in 1 Second over Time in COPD [PDF]
A key feature of chronic obstructive pulmonary disease (COPD) is an accelerated rate of decline in forced expiratory volume in 1 second (FEV(1)), but data on the variability and determinants of this change in patients who have established disease are scarce.We analyzed the changes in FEV(1) after administration of a bronchodilator over a 3-year period ...
Vestbo, Jorgen+17 more
openaire +7 more sources
Background: The pathogenesis of pulmonary senescence involves immune system dysregulation, oxidative stress, and mitochondrial dysfunction. The effects on lung function of niacin, an essential coenzyme involved in mitochondrial energy metabolism with ...
Xiaoli Xu+4 more
doaj +1 more source
Airways oxidative stress, lung function and cognitive impairment in aging. [PDF]
BACKGROUND: An altered balance of oxidants/antioxidants is one of the pathological mechanisms of many age-dependent disorders. We aimed to investigate the age-related airways oxidative stress, using non invasive, safe and repeatable techniques; to ...
Cagnazzo, Mg+5 more
core +1 more source
Prognostic Role of Pulmonary Function in Patients With Heart Failure With Reduced Ejection Fraction
Background Both ventilatory abnormalities and pulmonary hypertension (PH) are frequently observed in patients with heart failure with reduced ejection fraction.
Hao‐Chih Chang+7 more
doaj +1 more source
Non-infectious pulmonary complications of hematopoietic stem cell transplantation [PDF]
Noninfectious pulmonary complications of hematopoietic stem cell transplant are currently more prevalent than infectious complications. Unfortunately, the pathophysiology basis is not completely understood.
Baloglu, Orkun+2 more
core +1 more source
Issues of improving the functional training (different orientation of the training process) of athletes due the development of the respiratory system, including the respiratory system, as well as increasing the body's resistance to hypoxic stress remain ...
S. M. Kanyhina+2 more
doaj +1 more source
Relationships between estimated autozygosity and complex traits in the UK Biobank [PDF]
Inbreeding increases the risk of certain Mendelian disorders in humans but may also reduce fitness through its effects on complex traits and diseases. Such inbreeding depression is thought to occur due to increased homozygosity at causal variants that ...
Evans, Luke M+2 more
core +5 more sources
Longitudinal study of lung function in pregnant women: Influence of parity and smoking
OBJECTIVES: To evaluate pulmonary function in the first and third trimesters of pregnancy and analyze the influence of parity and smoking on spirometry parameters. METHODS: This longitudinal prospective study included a cohort of 120 pregnant women. The
Luciana Duzolina Manfré Pastro+7 more
doaj +1 more source
Gas exchange during exercise in habitually active asthmatic subjects [PDF]
We determined the relations among gas exchange, breathing mechanics, and airway inflammation during moderate- to maximum-intensity exercise in asthmatic subjects.
Dempsey, JA+6 more
core +1 more source