Results 51 to 60 of about 8,512,443 (291)

Prediction of postoperative cardiopulmonary complications after lung resection in a Chinese population: A machine learning-based study

Frontiers in Oncology, 2022
BackgroundApproximately 20% of patients with lung cancer would experience postoperative cardiopulmonary complications after anatomic lung resection. Current prediction models for postoperative complications were not suitable for Chinese patients.
Guanghua Huang, Lei Liu, Luyi Wang, Shanqing Li   +3 more
doaj   +1 more source

Effect of lung volume on forced expiratory flows during rapid thoracoabdominal compression in infants

, 1995
The rapid thoracoabdominal compression (RTC) technique is commonly used in pulmonary function laboratories to assess flow-volume relationships in infants unable to produce a voluntary forced expiration maneuver. This technique produces forced expiratory
C. J. Newth, J. Hammer
core   +1 more source

AARS1‐Mediated RUNX3 K193 Lactylation Enhances the Activation and Cytotoxicity of CD8+T Cells in Smoking‐Related Emphysema

Advanced Science, EarlyView.
Exposure to CS causes an elevation of AARS1 levels, which increases the levels of RUNX3 lactylation at the K193 site and increases protein levels of RUNX3 through inhibition of autolysosomal degradation. Elevated RUNX3 levels promote CD8+T cell activation and augment their cytotoxicity, which induces alveolar epithelial cell death and facilitates the ...
Ying Zhu, Jiaheng Lin, Yifan Li, Qiaoqiao Zhou, Min Yu, Cheng Cheng, Kang Chang, Dang Lin, Tao Bian, Yan Wu, Lu Lu, Haibo Xia, Qizhan Liu   +12 more
wiley   +1 more source

Patterns of dietary intake and relation to respiratory disease, forced expiratory volume in 1 s, and decline in 5-y forced expiratory volume [PDF]

The American Journal of Clinical Nutrition, 2010
The independent effect of individual foods on the risk of respiratory disease is difficult to establish because intakes of specific foods are generally strongly correlated. To date, few studies have examined the relation between dietary food patterns and forced expiratory volume in 1 s (FEV(1)) or respiratory symptoms.The objective was to investigate ...
Tricia M, McKeever, Sarah A, Lewis, Patricia A, Cassano, Marga, Ocké, Peter, Burney, John, Britton, Henriette A, Smit   +6 more
openaire   +2 more sources

A Biofabricated Human Acinus‐on‐a‐Chip Unveils Mechanotransductive Drivers of Ventilator‐Induced Lung Injury via Decoupling Volutrauma and Barotrauma

Advanced Science, EarlyView.
This bioinspired acinus‐on‐a‐chip recapitulates VILI pathology, revealing that volutrauma drives P53/NF‐κB pathways while barotrauma triggers mitochondrial‐Wnt dysregulation. A fibrotic transitional cell cluster was identified. Pharmacological interventions targeting these pathways significantly ameliorated injury, establishing a mechanobiological ...
Heng Lu, Liansheng Liu, Zengyong Hu, Shuxian Fang, Ruohan Ren, Sidi Liu, Meng Zhao, Zhiting Luo, Ziyue Zhang, Wenlong Shao, Qian Liu   +10 more
wiley   +1 more source

Assessment of pulmonary function among cleaners in governmental hospitals in Addis Ababa, Ethiopia; comparative cross-sectional study

BMC Research Notes, 2019
Objective Work-related disorders are the major causes of different diseases in working populations. Respiratory disorders are among the most common occupational diseases.
Biruk Getahun, Diresibachew W. Haile
doaj   +1 more source

ACAT1‐Mediated SP1‐K694 Lactylation Promotes M1 Macrophage Polarization via TREM1 Transcription in COPD

Advanced Science, EarlyView.
Upon cigarette smoke exposure(CSE), LDHA expression is increased in lung macrophages, promoting the conversion of pyruvate to lactate and elevating the lactylation level of SP1 at the K694 site. This, in turn, enhances SP1 enrichment at the TREM1 promoter, increases TREM1 expression, promoted M1 macrophage polarization, and triggers the secretion of ...
Ling Lin, Ping Zhang, Qing Song, Tao Li, Yuqin Zeng, Ping Chen   +5 more
wiley   +1 more source

Sources of variation in forced expiratory volume in one second and forced vital capacity [PDF]

European Respiratory Journal, 2006
Published prediction equations for lung function differ considerably, but the components of population variation responsible for the differences are unknown.Data were analysed for 6,323 never-smoking adults who did not report wheeze or asthma, from 42 centres participating in the European Community Respiratory Health Survey.
S, Chinn, D, Jarvis, C, Svanes, P, Burney   +3 more
openaire   +2 more sources

Low birth weight for gestation and airway function in infancy: exploring the fetal origins hypothesis [PDF]

, 2004
Background: Poor fetal growth has been associated with impaired airway function in adult life, but evidence linking birth weight and airway function in early childhood is sparse.
Lum, S, Costeloe, K, Hoo, AF, Hawdon, J, Stocks, J, Dezateux, C   +5 more
core  

Small size at birth and greater postnatal weight gain: relationships to diminished infant lung function

, 2004
Recent evidence suggests that impaired lung development is linked with diminished lung function and an increased risk of chronic obstructive airway disease in adulthood.
Gregson, Rachael K., Lucas, Jane S., Clough, Joanne B., Foreman, Claire T., Warner, John O., Inskip, Hazel M., Godfrey, Keith M.   +6 more
core   +1 more source