Guanylyl cyclase activation reverses resistive breathing–induced lung injury and inflammation [PDF]
Inspiratory resistive breathing (RB), encountered in obstructive lung diseases, induces lung injury. The soluble guanylyl cyclase (sGC)/cyclic guanosine monophosphate (cGMP) pathway is down-regulated in chronic and acute animal models of RB, such as ...
Brouckaert, Peter +15 more
core +2 more sources
ObjectiveRegular physical activity may be associated with improved lung function via reduced systemic inflammation, although studies exploring this mechanism are rare.
Elaine Fuertes +16 more
doaj +1 more source
Design and Benchmark Testing for Open Architecture Reconfigurable Mobile Spirometer and Exhaled Breath Monitor with GPS and Data Telemetry. [PDF]
Portable and wearable medical instruments are poised to play an increasingly important role in health monitoring. Mobile spirometers are available commercially, and are used to monitor patients with advanced lung disease.
Davis, Cristina E +7 more
core +2 more sources
Quantitative CT analysis in patients with pulmonary emphysema: is lung function influenced by concomitant unspecific pulmonary fibrosis? [PDF]
Purpose: Quantitative analysis of CT scans has proven to be a reproducible technique, which might help to understand the pathophysiology of chronic obstructive pulmonary disease (COPD) and combined pulmonary fibrosis and emphysema.
Doellinger, Felix +5 more
core +1 more source
Patterns of dietary intake and relation to respiratory disease, forced expiratory volume in 1 s, and decline in 5-y forced expiratory volume [PDF]
The independent effect of individual foods on the risk of respiratory disease is difficult to establish because intakes of specific foods are generally strongly correlated. To date, few studies have examined the relation between dietary food patterns and forced expiratory volume in 1 s (FEV(1)) or respiratory symptoms.The objective was to investigate ...
Tricia M, McKeever +6 more
openaire +2 more sources
OBJETIVO: Avaliar efetividade e rapidez de ação do formoterol liberado através de inalador para pó seco na reversão de broncoespasmo induzido pela metacolina.
Adalberto Sperb Rubin +4 more
doaj +1 more source
Background: Automobile industry is a place where workers are exposed to harmful chemicals and toxic substances. Workers engaged in automobile spray painting are at a risk of developing respiratory problems. This is due to exposure to low molecular weight compounds (isocyanates) in spray paints.
Geetika Gupta +4 more
openaire +2 more sources
Pharmacokinetics and pharmacodynamics of tiotropium solution and tiotropium powder in chronic obstructive pulmonary disease [PDF]
The aim of the study was to characterize pharmacokinetics of tiotropium solution 5 µg compared to powder 18 µg and assess dose-dependency of tiotropium solution pharmacodynamics in comparison to placebo.
Cornelissen, PJG +7 more
core +1 more source
Effectiveness and Safety of Oral Triamcinolone in the Management of Acute Exacerbations of Asthma: A Prospective Interventional Study [PDF]
Introduction: Acute exacerbation of asthma leads to increased morbidity, mortality, and healthcare costs. Oral Corticosteroids (OCS) are critical in the management of asthma exacerbations; however, the response varies between patients.
Santhalingam Balamurugan
doaj +1 more source
New reference ranges for interpreting forced expiratory manoeuvres in infants and implications for clinical interpretation: a multicentre collaboration [PDF]
The raised volume rapid thoracoabdominal compression (RVRTC) technique is commonly used to obtain full forced expiratory manoeuvres from infants, but reference equations derived from 'in-house' equipment have been shown to be inappropriate for current ...
Borrego, LM +12 more
core +1 more source

