Forced Migration, The Human Face of a Health Crisis [PDF]
, 2015 Nearly 60 million refugees, asylum-seekers and internally displaced persons (IDPs) fled their homes in 2014, predominately from war-torn Syria, Afghanistan and Somalia. The global response to assisting this vulnerable group has been wholly incommensurate
Gostin, Lawrence O., Roberts, Anna E.
core +2 more sources
Divergent discourses, children and forced migration [PDF]
, 2017 Experiences of refugee, internally displaced and migrant children in different contexts (such as post-conflict and resettlement) are often considered separately, yet closer analysis points to the existence of commonalities across transnational locations ...
Doná, Giorgia, Veale, Angela
core +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Rethinking Roma Migration in the Light of Recent Flow of Refugees to Canada from Three Central Eastern European Countries the Czech Republic, Hungary and Slovakia [PDF]
, 2013 The paper presents the research results of a pilot project on the (forced) migration of Roma from three Central Eastern European countries – the Czech Republic, Hungary and Slovakia – to Canada in the course of the last ten to fifteen years.
Vidra, Zsuzsanna
core
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Microfluidic electro‐viscoelastic manipulation of extracellular vesicles
FEBS Open Bio, EarlyView.The electro‐viscoelastic manipulation as a potential method for separation of particles based on size. The particles introduced as a sheath flow migrate to the channel center under the influence of simultaneously applied electric field and pressure driven flow.
Seyedamirhosein Abdorahimzadeh +7 more
wiley +1 more source
The Institution of Gender-Based Asylum and Epistemic Injustice: A Structural Limit [PDF]
, 2018 One of the recent attempts to explore epistemic dimensions of forced displacement focuses on the institution of gender-based asylum and hopes to detect forms of epistemic injustice within assessments of gender related asylum applications.
Sertler, Ezgi
core +2 more sources
HSP70 governs permeability and mechanotransduction in primary human endothelial cells
FEBS Open Bio, EarlyView.HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez +5 more
wiley +1 more source
Correction to: (Re-)Construction of Identity and Belonging after Forced Migration: A Sociology of Knowledge Approach [PDF]
, 2022 openalex +1 more source