Results 51 to 60 of about 64,539 (206)

AI‐Driven Acceleration of Fluorescence Probe Discovery

Advanced Science, EarlyView.
We present PROBY, an AI model trained on large‐scale datasets to predict key photophysical properties and accelerate the discovery of target‐specific fluorescent probes. By screening a target‐annotated library, PROBY identifies candidate probes for diverse targets and could guide probe optimization, enabling a range of in vitro and in vivo imaging ...
Xuefeng Jiang, Yanbo Li, Xue Tian, Sen Yang, Ruina Luo, Cenxing Zhou, Yuxuan Liu, Jingying Hu, Sen Feng, Lu Gan, Chongzhao Ran, Kun‐Hsing Yu, Junhan Zhao, Xiao Han, Xuan Zhai, Yuntao Jia, Jiapei Dai, Xiyue Wang, Biyue Zhu   +18 more
wiley   +1 more source

3D Bioprinted Fat‐Myocardium Model Unravels the Role of Adipocyte Hypertrophy in Atrial Dysfunction

Advanced Science, EarlyView.
A human‐derived 3D bioprinted fat–myocardium model is developed to investigate how adipocyte hypertrophy drives atrial dysfunction in obesity. Palmitate‐induced adipocyte hypertrophy promotes adipose dysfunction that impairs atrial cardiomyocyte metabolism and electrophysiology through both paracrine and direct interactions. This platform recapitulates
Lara Ece Celebi, Pinar Zorlutuna
wiley   +1 more source

Joint UK Land Environment Simulator (JULES) Version 2.2 User Manual [PDF]

, 2010
The Joint UK Land Environment Simulator (JULES) is a computer model that simulates many soil and vegetation processes. This document describes how to run version 2.2 of JULES.
Clark, Douglas, Harris, Phil, Hendry, Margaret, Pryor, Matt   +3 more
core  

3D‐MOF‐Lattice Inspired Programmable Metamaterials Based on Reconfigurable Polyhedral Origami

Advanced Science, EarlyView.
A novel metamaterial design strategy: inspired by MOFs crystal networks, creating reconfigurable modular polyhedral units to overcome the limitations of traditional materials. These modules exhibit adjustable stiffness, bistability, and Poisson's ratio that can be adjusted from negative to positive values.
Xi Kang, Yangqin Zhang, Hongshuang Fan, Ziyan Xu, Yue Dong, Bing Li   +5 more
wiley   +1 more source

Dynamic Decoration of DNA Scaffolds for High‐Resolution Cancer Cell Subtyping

Advanced Science, EarlyView.
This study presents a dual‐mode imaging platform that utilizes self‐assembly and disassembly of DNA scaffolds for high‐resolution cancer cell detection. The structural rigidity of DNA scaffolds effectively prevents cellular internalization for over 300 min.
Xiaolin Hu, Jie Xie, Xinlin Guo, Liangting Wang, Zhengheng Yu, Xiaopei Qiu, Heng Li, Kang Wang, Xiaoxing Wang, Mingxuan Song, Junsong Guo, Wei Gu, Sergio Bernardini, Chaoyong Yang, Hong Zhang, Yang Luo   +15 more
wiley   +1 more source

Parametric design method of building structured cabling system oriented to data mining

IET Networks, EarlyView., 2022
This paper puts forward the method of secondary development and design software through the research of building structured cabling system (SCS), and uses data mining technology to carry out parametric design of building SCS. Then, the feasibility of the design is tested by comparing the data of the traditional design and the parametric design ...
Bing Wang, Wei Yue
wiley   +1 more source

Computer Vision Pipeline for Image Analysis for Freeze‐Fracture Electron Microscopy: Rosette Cellulose Synthase Complexes Case

Advanced Intelligent Discovery, EarlyView.
This paper presents a computer vision (deep learning) pipeline integrating YOLOv8 and YOLOv9 for automated detection, segmentation, and analysis of rosette cellulose synthase complexes in freeze‐fracture electron microscopy images. The study explores curated dataset expansion for model improvement and highlights pipeline accuracy, speed ...
Siri Mudunuri, Leala Carbonneau, Eric M. Roberts, Alison W. Roberts, Candace H. Haigler, Alexey V. Gulyuk, Yaroslava G. Yingling   +6 more
wiley   +1 more source

Aerodynamic heating in large cavities in an array of RSI tiles [PDF]

A large panel of reusable surface insulation (RSI) tiles including lost tile cavities was aerothermally tested in the Langley 8 foot high temperature structures tunnel to determine both the heat load within the cavities and the structural performance of ...
Hunt, L. R.
core   +1 more source

Torque‐Transmitting Architected Metamaterials for Flexible and Extendable Tubular Robotics

Advanced Intelligent Systems, EarlyView.
Soft and continuum robots commonly rely on fluid, tendon, or rod‐based power transmissions, to control robotic form and actuation. This study presents an architected structure, based on patterned straight‐line mechanisms, that enables simultaneous bending, extending, and torsionally rigid (BETR) transmission.
Sawyer Thomas, Aman Garg, Jeffery Lipton
wiley   +1 more source

Tendon‐Driven Compliant Wheel‐Less Snake Robot for Undulatory Locomotion Using Conformable Ground Contacts

Advanced Intelligent Systems, EarlyView.
This study presents a tendon‐driven compliant snake robot that uses globally applied vertical bending and axial twisting along its body to enable various gaits. Body deflection from compliance and weight passively generates the ground contact patterns required for locomotion.
Serdar Incekara, Seongil Kwon, Gangil Kwon, Junhyoung Ha   +3 more
wiley   +1 more source