Results 121 to 130 of about 166,660,675 (310)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Armored Force Command and Center. Army Ground Forces study no. 27.
, 2020 The history presented in this study is written from the point of view of officers who were directly responsible for the development of armor in the U.S. Army in World War II.
Historical Section, Army Ground Forces
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Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
, 2008 Observational records and climate projections provide abundant evidence that freshwater resources are vulnerable and have the potential to be strongly impacted by climate change, with wide-ranging consequences for human societies ...
Kundzewicz, Zbigniew +2 more
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, 2020 The history of the Army Ground Forces as a command was prepared during the course of the war and completed immediately thereafter. The studies prepared in Headquarters, Army Ground Forces, were written by professional historians, three of whom served as
Historical Section, Army Ground Forces; Greenfield, Kent Roberts
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Public Health and School Health Education: Aligning Forces for Change. [PDF]
Health Promot Pract, 2019 Birch DA, Auld ME.
europepmc +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
History of the United States Army Forces, Central Canada.
, 2010 The history of the United States Army Forces in Central Canada is presented here. The body of the history deals with the growth and establishment of the Headquarters of the Command in Winnipeg, Manitoba, Canada.
Headquarters, United States Armed Forces, Central Canada
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Operation instruction no. 7/1942, Allied Air Forces.
, 2022 All Allied Air Forces of the Southwest Pacific Area, serving in the Port Moresby area, are placed under the operational control of the General Officer commanding the New Guinea Force (all naval and military forces in that area will be similarly ...
Headquarters, Allied Air Forces; Bostock, W. D.
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