Results 101 to 110 of about 35,403 (305)

Processos de elaboração de criatividade, inovação e capital social: O caso de Almada

open access: yesRevista Crítica de Ciências Sociais, 2012
Cities nowadays face many different pressures which are forcing them to become economically competitive by attracting investment and employment. This, in turn, demands increasingly sophisticated resources.
Jorge Gonçalves, Inês Vilhena da Cunha
doaj   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

Insights into turbulent airflow structures in blind headings under different ventilation duct distances

open access: yesScientific Reports
The paper explores the 3D stationary vortex structure of turbulent airflow near the dead-end face of a blind heading, ventilated via a forcing ventilation system.
Mikhail Semin   +4 more
doaj   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

The CO2 inhibition of terrestrial isoprene emission significantly affects future ozone projections [PDF]

open access: yes, 2009
Simulations of future tropospheric composition often include substantial increases in biogenic isoprene emissions arising from the Arrhenius-like leaf emission response and warmer surface temperatures, and from enhanced vegetation productivity in ...
Pyle, John A.   +13 more
core  

Rethinking Social Contracts: Building Resilience in a Changing Climate

open access: yesEcology and Society, 2009
Social contracts play an important role in defining the reciprocal rights, obligations, and responsibilities between states and citizens. Climate change is creating new challenges for both states and citizens, inevitably forcing a rethinking of existing ...
Karen O'Brien   +2 more
doaj   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Home - About - Disclaimer - Privacy