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Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source
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Combination Forecasting of Fuzzy Forecast

2009 Sixth International Conference on Fuzzy Systems and Knowledge Discovery, 2009
In this paper, we first give three kinds of model of fuzzy forecasting: fuzzy linear regression forecasting?Quadratic polynomial fuzzy regression forecasting and fuzzy time series self-regression forecasting, then we introduce the Combination forecasting of fuzzy forecast?and give two kind of combination forecasting of fuzzy forecast, one is the linear
Ai-bing Ji, Yan-hua Qiao, Hong-jie Qiu
openaire   +2 more sources

Macroeconomic forecasts and microeconomic forecasters [PDF]

open access: possibleJournal of Economic Behavior & Organization, 2002
In the presence of principal-agent problems, published macroeconomic forecasts by professional economists may not measure expectations. Forecasters may use their forecasts in order to manipulate beliefs about their ability. I test a cross-sectional implication of models of reputation and information-revelation.
openaire   +1 more source

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