Results 81 to 90 of about 449,929 (285)

Global threat forecast 2019

open access: yesRevista UNISCI, 2019
The global terrorist and extremist threat is likely to persist in 2019 as the Islamic State (IS) go through a phase of re-adaptation and de-centralisation. The group has established clandestine and underground structures to survive in Iraq and Syria. Its
Rohan Gunaratna
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Study on Enhancing the Comprehensive Prevention Capability of Marine Disasters in Shandong Province

open access: yesHaiyang Kaifa yu guanli
Shandong Province, one of the regions in China most severely affected by marine disasters, faces multiple challenges including diverse disaster types, extensive geographical distribution, high frequency of occurrence, and significant economic losses ...
JI Chengzhen   +5 more
doaj  

Comparison of Summer Convective Parameters Calculated from ERA5 Reanalysis Data and Soundings in Beijing

open access: yes应用气象学报
To evaluate the applicability of ERA5 reanalysis data in severe convective weather in Beijing during summer, ERA5 reanalysis data and soundings of Beijing at 1400 BT from June to August during 2009-2023 are used to calculate convection parameters ...
Yang Yiya   +4 more
doaj   +1 more source

Forecaster’s utility and forecasts coherence [PDF]

open access: yes, 2018
I provide general frequentist framework to elicit the forecaster’s expected utility based on a Lagrange Multiplier-type test for the null of locality of the scoring rules associated to the probabilistic forecast. These are assumed to be observed transition variables in a nonlinear autoregressive model to ease the statistical inference.
openaire   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Multi-decadal high-resolution historical simulations with the ECMWF global atmosphere model

open access: yesScientific Data
This paper describes an ensemble of global atmosphere reference simulations covering the period 1980 to 2023 produced with the European Centre for Medium-Range Weather Forecasts (ECMWF) Integrated Forecasting System (IFS).
Matthias Aengenheyster   +11 more
doaj   +1 more source

Detecting and Predicting Forecast Breakdowns [PDF]

open access: yes
We propose a theoretical framework for assessing whether a forecast model estimated over one period can provide good forecasts over a subsequent period.
Rossi, Barbara, Giacomini, Raffaella
core  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

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