Results 71 to 80 of about 130,658 (268)

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu   +8 more
wiley   +1 more source

‘They Need to Hear You Say It’: Healthcare Professionals’ Perspectives on Barriers and Enablers to End‐of‐Life Discussions With Adolescents and Young Adults With Cancer

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT End‐of‐life conversations with adolescents and young adults (AYAs) with cancer rarely occur without the guidance of healthcare professionals. As a part of the ‘Difficult Discussions’ study, focused on palliative care and advance care planning discussions with AYAs with cancer, we investigated the factors that healthcare professionals identify ...
Justine Lee   +9 more
wiley   +1 more source

Study on Enhancing the Comprehensive Prevention Capability of Marine Disasters in Shandong Province

open access: yesHaiyang Kaifa yu guanli
Shandong Province, one of the regions in China most severely affected by marine disasters, faces multiple challenges including diverse disaster types, extensive geographical distribution, high frequency of occurrence, and significant economic losses ...
JI Chengzhen   +5 more
doaj  

Higher Temperatures Lead to More Melt-Freeze Crusts in Snowpacks in Cooler Regions of the Pacific Northwest

open access: yesARC Geophysical Research
Warming winters will lead to a greater fraction of rain falling in traditionally snowy areas. Here, we investigate the impact of these changes on snowpack stratigraphy, focusing specifically on the presence and duration of melt-freeze crusts.
Clinton Alden   +3 more
doaj   +2 more sources

Operational Application of Optical Flow Techniques to Radar-Based Rainfall Nowcasting

open access: yesAtmosphere, 2017
Hong Kong Observatory has been operating an in-house developed rainfall nowcasting system called “Short-range Warning of Intense Rainstorms in Localized Systems (SWIRLS)” to support rainstorm warning and rainfall nowcasting services.
Wang-chun Woo, Wai-kin Wong
doaj   +1 more source

Feasibility and Safety of High‐Dose Proton Re‐Irradiation in Recurrent Pediatric Central Nervous System Tumors: A Single‐Institution Retrospective Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Pediatric central nervous system (CNS) tumors often recur despite multimodality therapy. Although re‐irradiation (re‐RT) has historically been limited by concerns for severe late toxicities, modern techniques have renewed interest in this approach. Proton therapy provides dosimetric advantages that may enable curative re‐treatment with
Jin‐Ho Song   +15 more
wiley   +1 more source

Forecaster’s utility and forecasts coherence [PDF]

open access: yes, 2018
I provide general frequentist framework to elicit the forecaster’s expected utility based on a Lagrange Multiplier-type test for the null of locality of the scoring rules associated to the probabilistic forecast. These are assumed to be observed transition variables in a nonlinear autoregressive model to ease the statistical inference.
openaire   +1 more source

Analysis of geological problems and difficulties in restoration and treatment of karst environment on the Yunnan plateau

open access: yesCarsologica Sinica
The karst region of the Yunnan plateau is characterized by high altitudes, diverse landforms, variable meteorological and hydrological conditions, and strong internal and external dynamic geological processes.
Hua ZHANG   +5 more
doaj   +1 more source

Defining Roles in Pediatric Palliative Care: Perspectives From Oncology and Palliative Care Teams

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Early integration of pediatric palliative care (PPC) is associated with improved symptom management, quality of life, and healthcare utilization for children with cancer. Despite this, variation persists in how PPC is understood, operationalized, and integrated within pediatric oncology programs. In particular, ambiguity surrounding
Leeat Granek   +13 more
wiley   +1 more source

Feasibility and Preliminary Efficacy of Integrative Neuromuscular Training for Childhood Cancer Survivors: A Pilot Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survivors of childhood acute lymphoblastic leukemia (ALL) often exhibit early deficits in muscle and movement competence, which can compromise long‐term health. Integrative neuromuscular training (INT), a multifaceted approach combining fundamental movement activities with strength exercises, may help address these deficits during ...
Anna Maria Markarian   +7 more
wiley   +1 more source

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