Results 121 to 130 of about 1,405,457 (345)

Spatial-temporal Graph Attention Networks for Traffic Flow Forecasting

, 2020
Chang Wei, Sheng Jin
openalex   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Temperature Monitoring and Forecast System in Remote Areas with 4.0G LTE Mobile Technologies [PDF]

, 2018
Kevin Alexandre Riaño Vargas, Octavio José Salcedo Parra, Miguel J. Espitia R.   +2 more
openalex   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Applying Weather Analyses and Forecasts in the Navy Decision-making Process [PDF]

, 1992
Samson Brand
openalex   +1 more source

Peer Review #1 of "Time series data analysis and ARIMA modeling to forecast the short-term trajectory of the acceleration of fatalities in Brazil caused by the corona virus (COVID-19) (v0.2)"

, 2021
Vrijesh Tripathi, Akini James, J Carcione, J Santos, C Bagaini, J Ba, C Chan, Gch Chan, T Leeper, J Becker, X Chen, B Yu, R Cleveland, W Cleveland, J Mcrae, I Terpenning, N Cohn, J Katz, M Sanger-Katz, K Quealy, E Dong, H Du, L Gardener, C Feng, H Wang, N Lu, T Chen, H He, Y Lu, X Tu, M Gardener, R Hyndman, R Hyndman, G Athanasopoulos, C Bergmeir, G Caceres, L Chhay, O 'hara-Wild, M Petropoulos, F Razbash, S Wang, E Yasmeen, F, R Hyndman, Y Khandakar, Adrian Trapletti, Kurt Hornik, A Keshvani, K Mclaughlin, R Nau, D Nykamp, K Roosa, Y Lee, R Luo, A Kirpich, R Rothenberg, J Hayman, P Yan, G Chowell, F Taspinar, N Celebi, N Tutkun, Y Utsunomiya, Ath Utsunomiya, Rbp Torrechilha, S Paulan, M Milanesi, J Garcia, A Veloso, N Ziviani, H Wickham, M Averick, J Bryan, W Chang, L Mcgowan, R Franois, G Grolemund, A Hayes, L Henry, J Hester, M Kuhn, T Pedersen, E Miller, S Bache, K Mller, J Ooms14, D Robinson, D Seidel, V Spinu, K Takahashi, D Vaughan, C Wilke, K Woo, H Yutani, Worldometer   +94 more
openalex   +2 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

The "Dobrescu Macromodel" of the Romanian Market Economy - 2005 Version - Yearly Forecast – Autumn Forecast 2011, September Estimate [PDF]

The macromodel estimates the short and medium-term economic implications for internal policies and changes in the international context. This version of the Romanian macromodel incorporates the experience accumulated through the utilization of its ...
Centre for Macroeconomic Modelling, Institute for Economic Forecasting   +1 more
core  

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source