Results 211 to 220 of about 2,067,646 (378)

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Automated water demand forecasting for national-scale deployment: a prophet-based framework for Palestinian municipal water management. [PDF]

Sci Rep
Salman A, Shaka'a Y.
europepmc   +1 more source

Robust Testing of the Utility‐based High‐technology Product Sales Forecasting Models Proposed by Decker and Gnibba‐Yukawa (2010) [PDF]

, 2012
Paul Goodwin, Sheik Meeran
openalex   +1 more source

FORECASTING FROSTS [PDF]

Monthly Weather Review, 1919
openaire   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

A new automatic forecasting method based on explainable deep dendritic artificial neural network. [PDF]

Sci Rep
Bas E, Egrioglu E.
europepmc   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Forecasting Influenza Epidemics and Pandemics in the Age of AI and Machine Learning. [PDF]

Rev Med Virol
Kamyshnyi O, Halabitska I, Oksenych V, Kamyshna I, Petakh P, Kainov DE.   +5 more
europepmc   +1 more source

Financial Conditions Index's Construction and its Application on Financial Monitoring and Economic Forecasting

, 2014
Guihuan Zheng, Yu Wang
openalex   +1 more source

EMPIRICAL MODE DECOMPOSITION BASED ON THETA METHOD FOR FORECASTING DAILY STOCK PRICE

, 2020
Mohammad Raquibul Hossain, Mohd Tahir Ismail   +1 more
openalex   +2 more sources