TREX1, a predator for treating MSI‐H tumors?
Molecular Oncology, EarlyView.Immunotherapy benefits many patients; yet, some with MSI‐H tumors remain unresponsive despite their high immunogenicity. Xu et al. reveal that TREX1 enables immune evasion by degrading cytosolic DNA and suppressing cGAS–STING–IFN‐I signaling. TREX1 loss restores DNA sensing, increases CD8+ T and NK cell infiltration, and boosts antitumor immunity ...
Elena Benidovskaya +2 more
wiley +1 more source
Cyber-resilient machine learning framework for accurate individual load forecasting and anomaly detection in smart grids. [PDF]
Sci RepTayseer M +8 more
europepmc +1 more source
Short-Term Electricity Price Forecasting Based on Grey Prediction GM(1,3) and Wavelet Neural Network [PDF]
, 2018 Jun Dong
openalex +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Integrated forecasting and deep reinforcement learning for price-based self-scheduling of PV-BESS: Utility-scale evidence in Chile. [PDF]
PLoS OnePérez J, Lobos G, Bonacic M.
europepmc +1 more source
Mathematical Models for Natural Gas Forecasting
, 2009 Steven R. Vitullo +3 more
openalex +1 more source
Neural Network Optimized by Genetic Algorithm of Models for Real-Time Forecast of Traffic Flow [PDF]
, 2010 Jun Hai-min, Yulong Pei
openalex +1 more source
A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy
Molecular Oncology, EarlyView.Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti +3 more
wiley +1 more source
A dual-domain seasonal hybrid forecasting strategy for PV power considering dynamic uncertain fluctuations. [PDF]
Sci RepYuan Z, Xu Y, Xie S, Zhang Z.
europepmc +1 more source