Results 61 to 70 of about 139,006 (249)
Uncertainty quantification (UQ) is critical for modeling complex dynamic systems, ensuring robustness and interpretability. This study extends Physics-Guided Bayesian Neural Networks (PG-BNNs) to enhance model robustness by integrating physical laws into
Xinyue Xu, Julian Wang
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Exchange Rates, Supply Chain Activity/Disruption Effects, and Exports
In the past, South African monetary policy aimed to protect the external value of the domestic currency (Rand); however, these efforts failed. Later, its monetary policy approach changed to allow the foreign exchange rate market to determine the exchange
Simiso Msomi, Paul-Francios Muzindutsi
doaj +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Testing for Bias in Forecasts for Independent Multinomial Outcomes
This paper deals with a test on forecast bias in predicting independent multinomial outcomes where the predictions are probabilities. The new Likelihood Ratio (and Wald) test extends the familiar Mincer Zarnowitz regression to a multinomial logit model ...
Philip Hans Franses, Richard Paap
doaj +1 more source
There has been a great deal of speculation in the media about whether or not there are genuine signs of economic recovery in the UK--the now infamous 'Green Shoots'. Although economic growth is picking up, the rate of acceleration is still very weak. Despite this, many commentators are forecasting that the rate of economic growth will steadily increase
openaire +2 more sources
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Heavy Rainfall Events in Selected Geographic Regions of Mexico, Associated with Hail Cannons
In this article, we document the use of hail cannons in Mexico to dispel or suppress heavy rain episodes, a common practice among farmers, without scientific evidence to support its effectiveness. This study uses two rain databases: one compiled from the
Victor M. Rodríguez-Moreno +1 more
doaj +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Transportation significantly influences greenhouse gas emissions—particularly carbon dioxide (CO2)—thereby affecting climate, health, and various socioeconomic aspects. Therefore, in developing and implementing targeted and effective policies to mitigate
Thananya Janhuaton +2 more
doaj +1 more source

