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Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Exchange Rates, Supply Chain Activity/Disruption Effects, and Exports
In the past, South African monetary policy aimed to protect the external value of the domestic currency (Rand); however, these efforts failed. Later, its monetary policy approach changed to allow the foreign exchange rate market to determine the exchange
Simiso Msomi, Paul-Francios Muzindutsi
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Testing for Bias in Forecasts for Independent Multinomial Outcomes
This paper deals with a test on forecast bias in predicting independent multinomial outcomes where the predictions are probabilities. The new Likelihood Ratio (and Wald) test extends the familiar Mincer Zarnowitz regression to a multinomial logit model ...
Philip Hans Franses, Richard Paap
doaj +1 more source
Forecasting overhead distribution line failures using weather data and gradient-boosted location, scale, and shape models [PDF]
Antoni M. Sieminski, Carl Donovan
openalex +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Heavy Rainfall Events in Selected Geographic Regions of Mexico, Associated with Hail Cannons
In this article, we document the use of hail cannons in Mexico to dispel or suppress heavy rain episodes, a common practice among farmers, without scientific evidence to support its effectiveness. This study uses two rain databases: one compiled from the
Victor M. Rodríguez-Moreno +1 more
doaj +1 more source
The "Dobrescu Macromodel" of the Romanian Market Economy - 2005 Version Yearly Forecast Summer Forecast 2009 [PDF]
The macromodel estimates the short and medium-term economic implications for domestic policies and changes in the international context. This version of the Romanian macromodel incorporates the experience accumulated through the utilisation of its ...
Institute for Economic Forecasting
core
There has been a great deal of speculation in the media about whether or not there are genuine signs of economic recovery in the UK--the now infamous 'Green Shoots'. Although economic growth is picking up, the rate of acceleration is still very weak. Despite this, many commentators are forecasting that the rate of economic growth will steadily increase
openaire +2 more sources

