Results 61 to 70 of about 146,575 (268)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Testing for Bias in Forecasts for Independent Multinomial Outcomes

open access: yesForecasting
This paper deals with a test on forecast bias in predicting independent multinomial outcomes where the predictions are probabilities. The new Likelihood Ratio (and Wald) test extends the familiar Mincer Zarnowitz regression to a multinomial logit model ...
Philip Hans Franses, Richard Paap
doaj   +1 more source

Performance Forecasting

open access: yes, 2009
Schon seit mehreren Jahrzehnten wird bei meisten Unternehmen Performance Tuning von Rechnersystemen betrieben. Dieses Thema wurde wie von der Seite der Unternehmen als auch von der Wissenschaft mittlerweile in zahlreichen unterschiedlichen Aspekten erforscht und ausgearbeitet.
Tropmann-Frick, Marina   +2 more
openaire   +3 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Heavy Rainfall Events in Selected Geographic Regions of Mexico, Associated with Hail Cannons

open access: yesForecasting
In this article, we document the use of hail cannons in Mexico to dispel or suppress heavy rain episodes, a common practice among farmers, without scientific evidence to support its effectiveness. This study uses two rain databases: one compiled from the
Victor M. Rodríguez-Moreno   +1 more
doaj   +1 more source

Forecasting volatility [PDF]

open access: yesJournal of Futures Markets, 1999
The forecasting ability of the most popular volatility forecasting models is examined and an alternative model developed. Existing models are compared in terms of four attributes: (1) the relative weighting of recent versus older observations, (2) the estimation criterion, (3) the trade-off in terms of out-of-sample forecasting error between simple and
Ederington, Louis H., Guan, Wei
openaire   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Forecasting Thailand’s Transportation CO2 Emissions: A Comparison among Artificial Intelligent Models

open access: yesForecasting
Transportation significantly influences greenhouse gas emissions—particularly carbon dioxide (CO2)—thereby affecting climate, health, and various socioeconomic aspects. Therefore, in developing and implementing targeted and effective policies to mitigate
Thananya Janhuaton   +2 more
doaj   +1 more source

Defensive forecasting [PDF]

open access: yesCoRR, 2005
We consider how to make probability forecasts of binary labels. Our main mathematical result is that for any continuous gambling strategy used for detecting disagreement between the forecasts and the actual labels, there exists a forecasting strategy whose forecasts are ideal as far as this gambling strategy is concerned.
Vovk, Vladimir   +2 more
openaire   +10 more sources

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

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