Results 81 to 90 of about 536,403 (288)

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Demand Forecasting for Water Distribution Systems

open access: yesProcedia Engineering, 2014
AbstractShort-term water demand forecasts can provide valuable information to distribution system operators for controlling the produc- tion, storage and delivery of drinking water. Our current research is focused on developing an integrated Time Series Forecasting Framework (TSFF) to statistically predict hourly/quarter-hourly demands in real-world ...
Chen, J., Boccelli, D.L.
openaire   +1 more source

NoVaS Transformations: Flexible Inference for Volatility Forecasting [PDF]

open access: yes
In this paper we contribute several new results on the NoVaS transformation approach for volatility forecasting introduced by Politis (2003a,b, 2007).
Dimitrios D. Thomakos   +1 more
core  

Optimal Dispatch of Residential Photovoltaic Inverters Under Forecasting Uncertainties

open access: yes, 2014
Efforts to ensure reliable operation of existing low-voltage distribution systems with high photovoltaic (PV) generation have focused on the possibility of inverters providing ancillary services such as active power curtailment and reactive power ...
Dall'Anese, Emiliano   +3 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Managing Livestock Feed Cost Risks Using Futures and Options [PDF]

open access: yes
The costs of corn- and soybean-based feeds compose a substantial proportion of the variable costs faced by both mainstream and emergent confined livestock producers.
Chen, Gang   +2 more
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Quantile Forecasts of Daily Exchange Rate Returns from Forecasts of Realized Volatility [PDF]

open access: yes
Quantile forecasts are central to risk management decisions because of the widespread use of Value-at-Risk. A quantile forecast is the product of two factors : the model used to forecast volatility, and the method of computing quantiles from the ...
Clements, Michael P.   +2 more
core  

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Deep learning and smart energy-based lightweight urban power load forecasting model for sustainable urban growth

open access: yesFrontiers in Sustainable Cities
IntroductionUrban power load forecasting is essential for smart grid planning but is hindered by data imbalance issues. Traditional single-model approaches fail to address this effectively, while multi-model methods mitigate imbalance by splitting ...
Haewon Byeon   +5 more
doaj   +1 more source

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