Results 151 to 160 of about 219,144 (273)

The geometry of pMHC‐coated nanoparticles and T‐cell receptor clusters governs the sensitivity‐specificity trade‐off in T‐cell response: a modeling investigation

open access: yesImmunology &Cell Biology, EarlyView.
Using numerical Monte Carlo simulations of nanoparticle‐T‐cell receptors binding, we show that the spatial organization of surface receptors is important for affinity‐based discrimination of peptide‐major histocompatibility complex ligands. Interaction geometry modulates the sensitivity of the T‐cell response to both ligand concentration and binding ...
Louis Richez, Anmar Khadra
wiley   +1 more source

Tissue Resident Memory Cells: Friend or Foe?

open access: yesImmunology, EarlyView.
Tissue‐resident memory T cells (TRM cells) are specialised immune cells in barrier tissues like the lungs, skin and gut, providing rapid host defence and tumour surveillance. Their retention and differentiation are regulated by molecules such as CD69, CD103 and TGF‐β. Dysregulation of TRM cells can lead to chronic activation, driving conditions such as
Chidimma F. Chude   +2 more
wiley   +1 more source

Exploring the Role of Ideology and Sectoral Power for Trade Unions' Social Partnership Choices in Liberal Market Economies

open access: yesIndustrial Relations: A Journal of Economy and Society, EarlyView.
ABSTRACT While scholars have often debated the outcomes of partnership strategy, they have rarely studied the conditions in which trade unions opt to pursue partnerships, especially social partnerships in liberal market economies (‘LMEs’). By comparing five trade unions' social partnership responses in the US‐American and English healthcare systems ...
Nick Krachler
wiley   +1 more source

Cultivating Nurse Leaders: Integrating Policy Analysis Projects in Doctor of Nursing Practice Programmes

open access: yesJournal of Advanced Nursing, EarlyView.
ABSTRACT Aim To present the process of establishing a Doctor of Nursing Practice (DNP) policy analysis project option at one nursing school, offering examples of diverse student and graduate analyses to guide other institutions. Background Nurses are skilled patient advocates, and their advocacy forms a crucial foundation for influencing health policy.
Elizabeth K. Kuzma   +10 more
wiley   +1 more source

Cultural Beliefs and Practices of Internationally Educated Nurses in the Context of Cancer and End‐Of‐Life Care: A Hermeneutic Inquiry

open access: yesJournal of Advanced Nursing, EarlyView.
ABSTRACT Aims This study aimed to (1) gain an understanding of the experiences of IENs in providing cancer and end‐of‐life care; (2) explore their cultural beliefs and practices and analyse how their experiences, beliefs, and practices shape approaches to nursing care within this care context. Design Hermeneutic inquiry.
Jay Balante   +2 more
wiley   +1 more source

An Arrested Virtuous Circle? Higher Education And High-Tech Industries In India [PDF]

open access: yes
We provide a brief but comprehensive overview of linkages between higher education and the high tech sector and study the major linkages in India. We find that the links outside of the labor market are weak.
Basant, Rakesh, Partha Mukhopadhyay
core  

Navigating Prediabetes in a Foreign Country: A Qualitative Study of Self‐Management Experiences Among Chinese‐Speaking Immigrants in Australia

open access: yesJournal of Advanced Nursing, EarlyView.
ABSTRACT Aim Chinese‐speaking immigrants in Australia have a higher risk of type 2 diabetes and face more barriers to accessing quality healthcare compared to non‐culturally and linguistically diverse populations. This study aimed to explore the self‐management experiences of Chinese‐speaking Australians with self‐reported lived experience of ...
Min Zhang   +3 more
wiley   +1 more source

Understanding the link between adolescent depression and precarious employment in adulthood: evidence from a sibling fixed effects analysis

open access: yesJournal of Child Psychology and Psychiatry, EarlyView.
Background Adolescent depressive symptoms may mark the beginning of long‐term trajectories of socioeconomic disadvantage, yet their role in shaping labor market outcomes remains understudied. This study investigates the longitudinal association between depressive symptoms in adolescence and precarious employment in adulthood and explores the mediating ...
Jinho Kim   +3 more
wiley   +1 more source

Expectations for Families to Care for Older Adults in the United States: Rapid Scoping Review 2011–2023

open access: yesJournal of Family Theory &Review, EarlyView.
ABSTRACT As the population ages and families become increasingly diverse, more work is needed to understand expectations for families to care for older adults. In this review, we discuss the theoretical frameworks and conceptualizations used to study care expectations, summarize overarching findings about theories of care expectations and corresponding
Sarah E. Patterson   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy