Results 51 to 60 of about 108,865 (249)

EEPD1 Inhibition Unleashes Antitumor Immunity in Colorectal Cancer by Activating the cGAS‐STING Pathway

Advanced Science, EarlyView.
In colorectal cancer, high expression of the DNA repair protein EEPD1 correlates with immune exclusion and poor prognosis. This study demonstrates that EEPD1 depletion induces genomic instability, leading to cytosolic DNA accumulation and subsequent activation of the cGAS‐STING‐type I interferon pathway. This cascade remodels the tumor microenvironment
Liyun Huo, Chong Wu, Xiaobo Li, Caina Ma, Jiamin Huang, Zishuo Chen, Weiling He, Tianyu Tao, Weijing Zhang   +8 more
wiley   +1 more source

Relationship Between CVMI and Dental Calcification Stages

Journal of Pharmacy and Bioallied Sciences
Background: Assessment of skeletal and dental maturation (DM) is a commonly applied approach in dental practice for growth modification. The main objective of the study is to find the relationship between the cervical vertebral maturation index (CVMI ...
Anushri Bhardwaj, Sheron Bhanat, Mahishi G. Suthar, Shatha Ahmad Mohammad Jafari, Shreya Daga, Manoj Meena, Akshaya Ojha   +6 more
doaj   +1 more source

“Will you be there for me?” Social support from family and friends during cold case sexual assault prosecutions

American Journal of Community Psychology, EarlyView.
Abstract If sexual assault survivors report the assault to the criminal legal system, they often need informal support from family and friends throughout the long and frequently retraumatizing process of investigation and prosecution. This study is part of a long‐term community‐based participatory action research project in a predominately Black ...
Rebecca Campbell, Rachael Goodman‐Williams, Katie Gregory, McKenzie Javorka, Jasmine Engleton   +4 more
wiley   +1 more source

Forensic and pharmaceutical research of organization of availability of the medicines for patients with malignancies in the United States

Annals of Mechnikov's Institute, 2020
Introduction. The incidence of cancer in recent years has increased significantly. It is therefore particularly important today is the issue of provision for patients with malignancies with drugs.
V (Jr.) Shapovalov, S Zbrozhek, V Shapovalova, V Shapovalov, O Kulykova   +4 more
doaj  

Measuring Child Disadvantage: Comparing Multidimensional and Socioeconomic Approaches for Predicting Developmental Outcomes

Australian Journal of Social Issues, EarlyView.
ABSTRACT Robust measurement of disadvantage is essential to identifying and addressing inequities in children's development. We tested how a multidimensional framework of child disadvantage performed relative to a traditional socioeconomic position (SEP) approach to predict developmental outcomes.
Wei Hong, Fiona Mensah, Elodie O'Connor, Shuaijun Guo, Sharon Goldfeld, Meredith O'Connor, Cindy Pham, Sarah Gray   +7 more
wiley   +1 more source

Body Measurements for Digital Forensic Comparison of Individuals—An Overview of Current Developments

Applied Sciences
Forensic identification of individuals faces significant challenges, particularly when conventional biometric features such as the face are hidden.
Sabine Richter, Dirk Labudde
doaj   +1 more source

Forensic within the Framework of Expert-Analytical and Auditing Activities: Theoretical Research of the Concept

Учёт. Анализ. Аудит, 2019
Topic. Economic development along with an increase in the number of companies leads to the growth of the number of economic (financial) crimes, including various types of fraud.
Mikhail A. Gorodilov, Natalya A. Shklyaeva   +1 more
doaj   +1 more source

An ultra‐processed food‐based cafeteria diet induces obesity, metabolic dysfunction, and tissue‐specific gene dysregulation in C57BL/6 mice

Animal Models and Experimental Medicine, EarlyView.
This schematic figure illustrates the experimental design and key findings of the study. Forty male C57BL/6 mice were assigned to either a standard diet control group or a cafeteria diet (CAFD) group for 16 weeks. CAFD induces obesity, insulin resistance (HOMA‐IR), hepatic steatosis, and dysregulation of a number of genes in visceral and subcutaneous ...
Guilherme Coutinho Kullmann Duarte, Daisy Crispim, Shiva Cerutti Wittée, Joana Raquel Nunes Lemos, Natalia Emerim Lemos, Mayara Souza de Oliveira, Melissa Daniele Alves, Eloísa Toscan Massignam, Tais Silveira Assmann, Felipe Mateus Pellenz   +9 more
wiley   +1 more source

Child and Adolescent Suicide in the Broader Area of Athens, Greece: A 13-Year Retrospective Forensic Case-Series Analysis

Pediatric Reports
Purpose: Suicide is a leading cause of death among children and adolescents worldwide. This study examined the prevalence and characteristics of suicides among children and adolescents (aged ≤ 19 years) over a 13-year period in the broader area of Athens,
Kallirroi Fragkou, Maria Alexandri, Konstantinos Dimitriou, Athina Tatsioni, Flora Bacopoulou, Panagiotis Ferentinos, Laurent Martrille, Stavroula Papadodima   +7 more
doaj   +1 more source

Nanomaterial‐Mediated Near‐Infrared Photothermal Neuromodulation for Neurologic Disorders

Advanced NanoBiomed Research, EarlyView.
This review summarizes how near‐infrared light activates photothermal nanomaterials to enable noninvasive neuromodulation with high spatiotemporal precision. It elucidates the underlying mechanisms, explores targeted therapeutic applications for neurological disorders, discusses integration with optogenetics and biosensors, and addresses future ...
Ting‐Ting Zeng, Yu‐Ge Wang, Ya‐Bing Zhang, Yuan‐Xin Bai, Si‐Tong Lin, Ting‐Ting Zhu, Yan‐Bo Zhou, Wei‐Tong Pan, Pan‐Miao Liu, Jian‐Jun Yang   +9 more
wiley   +1 more source