Results 111 to 120 of about 13,227 (278)

Annual Banned‐Substance Review 18th Edition—Analytical Approaches in Human Sports Drug Testing 2024/2025

open access: yesDrug Testing and Analysis, EarlyView.
New insights into drug metabolism, distribution, elimination, and detection assays for drugs and methods of sports doping published between 2024 and 2025 are critically reviewed and evaluated in context with the Prohibited List 2025 as established by the World Anti‐Doping Agency.
Mario Thevis, Tiia Kuuranne, Hans Geyer
wiley   +1 more source

Evaluation of Therapeutic Opioids in Skin‐Derived Matrices (Sweat and Sebum) of Neonatal and Pediatric Patients and Their Role in Opioid Incorporation Into Hair

open access: yesDrug Testing and Analysis, EarlyView.
Concentration ranges, dose–concentration relationships, and metabolite‐to‐parent drug ratios of therapeutic opioids were evaluated in hair and skin swab samples of 150 pediatric patients. Skin‐derived matrices such as sweat or sebum were shown to contribute to analyte incorporation into hair in a systematic manner.
Max Polke   +7 more
wiley   +1 more source

The caring experiences of family caregivers for patients with advanced cancer in Uganda: A qualitative study. [PDF]

open access: yesPLoS One, 2023
Najjuka SM   +10 more
europepmc   +1 more source

Identification of Metabolites of the Dietary Supplement Ingredient 5α‐Hydroxy‐Laxogenin

open access: yesDrug Testing and Analysis, EarlyView.
The biotransformation of the dietary supplement ingredient 5α‐hydroxy‐laxogenin was investigated using human HepG2 cells, the rat and in silico using the online software Next‐gen E‐Resource for Drug Discovery (NERDD). We identified five metabolites generated by the human HepG2 cells of which three and an additional mono‐hydroxylated metabolite were ...
Daniel Derwand   +3 more
wiley   +1 more source

Evaluating Transcriptomic Biomarkers for rHuEPO Detection: Assessing the Impact of Exercise and Altitude Exposure

open access: yesDrug Testing and Analysis, EarlyView.
A two‐stage transcriptomic filter comparing rHuEPO, exercise and altitude responses reduced 153 candidate genes to 50 that were unaffected by physiological stimuli. These retained transcripts offer focused biomarker leads to strengthen antidoping detection of rHuEPO.
Daria Obratov   +4 more
wiley   +1 more source

The characteristics of older homicide offenders: a systematic review. [PDF]

open access: yesPsychiatr Psychol Law, 2022
Nguyen H, Haeney O, Galletly C.
europepmc   +1 more source

Ethyl Glucuronide in Hair: A 10‐Year Overview

open access: yesDrug Testing and Analysis, EarlyView.
The present study builds on a unique collection of more than 68,000 hair EtG results collected in the Northen Italy between 2013 and 2022. We investigated trends in alcohol consumption in terms of age, gender, recidivism, applicants, sampling region, sampling length, across seasons, and the COVID‐19.
Sara Casati   +8 more
wiley   +1 more source

Bromazolam Tablet Quantification and Analysis of Post‐Mortem Cases From the National Programme on Substance Use Mortality (NPSUM)

open access: yesDrug Testing and Analysis, EarlyView.
Tablets submitted to drug checking services that were found to contain bromazolam. Over half of these counterfeit tablets mimicked the appearance of licensed formulations (e.g., alprazolam Xanax bars and diazepam Roche 10 mg pills). Bromazolam is now the most commonly detected street benzodiazepine in drug poisoning deaths in the United Kingdom ...
Matthew Gardner   +9 more
wiley   +1 more source

Isomer Composition Assessment of Synthetic Phosphatidylethanol by Collision‐Induced and Ozone‐Induced Dissociation Mass Spectrometry

open access: yesDrug Testing and Analysis, EarlyView.
This study examines the isomeric composition of PEth reference materials and compares it with the natural variation in isomer distribution found in blood samples. ABSTRACT The direct blood‐alcohol biomarker phosphatidylethanol (PEth), especially its most abundant analogue 1‐palmitoyl‐2‐oleoyl‐sn‐phosphatidylethanol (PEth 16:0/18:1) has gained ...
Matthias Bantle   +6 more
wiley   +1 more source

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