Results 41 to 50 of about 11,666 (259)
Advanced Science, EarlyView.This study generates high‐fidelity synthetic longitudinal records for a million‐patient diabetes cohort, successfully replicating clinical predictive performance. However, deeper analysis reveals algorithmic biases and trajectory inconsistencies that escape standard quality metrics. These findings challenge current validation norms, demonstrating why a
Francisco Ortuño +5 more
wiley +1 more source
Simulation of motor vehicle fires in forensic engineering [PDF]
NBP: Nauka, bezbednost, policija, 2017 Motor vehicle fires represent a specific field of research within scientific field of fire protection. A considerably larger part of this research is dedicated to the causes of vehicle fires and the manners of their detection.
Zigar Darko +2 more
doaj
On the Concept of Transportation Engineering Investigations
Теория и практика судебной экспертизы, 2018 The paper addresses the current need to develop a special theory of the category of transportation engineering investigations, which remains underexplored to date.
N. N. Il’in
doaj +1 more source
Advanced Science, EarlyView.This study reveals that chronic alcohol exposure selectively upregulates ACSL1 expression in prefrontal cortical microglia, driving lipid metabolism reprogramming and lipid droplet accumulation, which activates the NLRP3 inflammasome and sustains neuroinflammation. To reverse this process, a dual‐targeted lipid nanoparticle, siACSL1@LNP‐MR, is designed
Liang Hao +8 more
wiley +1 more source
BMC Genomics, 2023 Uniparental-inherited haploid genetic marker of Ychromosome single nucleotide polymorphisms (Y-SNP) have the power to provide a deep understanding of the human evolutionary past, forensic pedigree, and bio-geographical ancestry information.
Guang-Bin Zhao +11 more
doaj +1 more source
Advanced Science, EarlyView.We identified the endothelial RAP2A as a regulator of inflammatory endothelial activation in experimental lung fibrosis and suggest that targeting RAP2A‐mediated signaling may represent a potential strategy to modulate endothelial–immune crosstalk during fibrotic lung injury.
Xiaolan Zheng +13 more
wiley +1 more source
Advanced Science, EarlyView.BiSCALE: A pathology‐driven deep learning framework for multi‐scale gene expression prediction from whole‐slide images. It accurately infers bulk and near‐cellular spot‐level expression, links predictions to clinical phenotypes, identifies disease‐associated niches, and enables applications in risk stratification and cell‐identity annotation, providing
Hailong Zheng +8 more
wiley +1 more source
Advanced Science, EarlyView.A MXene‐enhanced electrochemical sensor enables the rapid and direct detection of methamphetamine. Molecular simulations reveal that specific MXene surface functional groups act as key signal amplifiers by facilitating interfacial interactions. The sensor demonstrates high sensitivity and robust performance in complex biological matrices.
Ri Wang +7 more
wiley +1 more source
Reply to “Comment on ‘De Novo Reconstruction of 3D Human Facial Images From DNA Sequence’”
Advanced Science, EarlyView.ABSTRACT This manuscript is a formal response to the Comment by Wagner et al. regarding our publication “De Novo Reconstruction of 3D Human Facial Images from DNA Sequence.” We clarify the methodological rationale, analytical procedures, and scientific scope of our original study, and we address several misconceptions arising in the Comment. We further
Mingqi Jiao +4 more
wiley +1 more source
Australian Journal of Social Issues, EarlyView.ABSTRACT Alcohol and other drug‐facilitated sexual violence can have significant impacts on victim‐survivors, yet little is known about what support service providers offer them. To understand the experiences and perceptions of service providers, interviews with counsellors, health workers, forensic toxicologists and harm reduction workers were ...
Jessica Ison +5 more
wiley +1 more source