Results 131 to 140 of about 14,072 (251)
Research progress on application of microhaplotype in forensic genetics. [PDF]
Zhejiang Da Xue Xue Bao Yi Xue Ban, 2021 Zhou J, Wang Y, Xu E.
europepmc +1 more source
Ion Activation Methods for Top‐Down Proteomics
Mass Spectrometry Reviews, EarlyView.ABSTRACT Mass spectrometry (MS) has emerged as a premier method used to characterize the sequences of proteins. Top‐down proteomics aims to capture the multiple sources of structural diversity reflected in proteins, such as those that arise from alternative RNA splicing events or the addition of post‐translational modifications. Tandem MS (i.e., MS/MS)
Jada N. Walker, Jennifer S. Brodbelt
wiley +1 more source
First 20 Years of Orbitrap Mass Spectrometry as the Mainstream Analytical Technique
Mass Spectrometry Reviews, EarlyView.ABSTRACT This review traces the first 20 years of Orbitrap mass spectrometry as a mainstream high‑resolution and accurate‑mass (HR/AM) technology. It outlines the historical development of the Orbitrap analyzer, the evolution of major instrument families, and the key technological innovations that enabled its widespread adoption. Particular emphasis is
Alexander Makarov
wiley +1 more source
Who killed my dog? Use of forensic genetics to investigate an enigmatic case. [PDF]
Int J Legal Med, 2021 Roccaro M +5 more
europepmc +1 more source
Recent Advances in Top‐Down Proteomics for Single‐Cell Research
Mass Spectrometry Reviews, EarlyView.ABSTRACT Individual cells have distinctive molecular characteristics, including biologically relevant proteoforms. Although single‐cell (SC) molecular omics offer unprecedented insights into cellular heterogeneity and function, the characterization of proteoforms in SCs remains an uncharted territory.
Jake A. Melby, Pei Su, Fabio P. Gomes
wiley +1 more source
Progress in the implementation of massively parallel sequencing for forensic genetics: results of a European-wide survey among professional users. [PDF]
Int J Legal Med, 2021 Gross TE, Fleckhaus J, Schneider PM.
europepmc +1 more source
Ferroptosis and Its Emerging Role in Gestational Diabetes Mellitus
Medicine Advances, EarlyView.Ferroptosis contributes to the development of gestational diabetes mellitus (GDM) through iron overload, lipid peroxidation, and antioxidant system disruption. These changes impair adipocyte and β‐cell function, promoting insulin resistance and hyperglycemia.
Jinfeng Xu +4 more
wiley +1 more source
Magnetic Resonance in Medicine, EarlyView.ABSTRACT Purpose Quantification of metabolite concentrations using MRS requires tissue‐dependent signal corrections. Accurate estimation of voxel tissue composition is therefore essential. Commonly used brain tissue segmentation tools differ in their algorithms and implementation, potentially introducing variability in MRS‐derived concentration ...
Jessica Archibald +12 more
wiley +1 more source
International Journal of Osteoarchaeology, EarlyView.ABSTRACT This paper presents the first documented case of a fixed bone dental bridge in Portugal. This item was recovered alongside the remains of a young adult individual of indeterminate sex from the 19th century burial site of the 3rd Order of Our Lady of Carmo in Porto, Portugal.
Steffi Vassallo +8 more
wiley +1 more source