Results 51 to 60 of about 65,263 (348)

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

open access: yesAdvanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa   +3 more
wiley   +1 more source

Using 3D CNN for classification of Parkinson’s disease from resting-state fMRI data

open access: yesJournal of Engineering and Applied Science, 2023
Parkinson’s disease is a chronic and progressive movement disorder caused by the degeneration of dopamine-producing neurons in the substantia nigra of the brain.
Nair Ul Islam   +2 more
doaj   +1 more source

Face recognition technologies for evidential evaluation of video traces [PDF]

open access: yes, 2017
Human recognition from video traces is an important task in forensic investigations and evidence evaluations. Compared with other biometric traits, face is one of the most popularly used modalities for human recognition due to the fact that its ...
Li, Chang-Tsun, Wei, Xingjie
core   +1 more source

High‐Fidelity Synthetic Data Replicates Clinical Prediction Performance in a Million‐Patient Diabetes Cohort

open access: yesAdvanced Science, EarlyView.
This study generates high‐fidelity synthetic longitudinal records for a million‐patient diabetes cohort, successfully replicating clinical predictive performance. However, deeper analysis reveals algorithmic biases and trajectory inconsistencies that escape standard quality metrics. These findings challenge current validation norms, demonstrating why a
Francisco Ortuño   +5 more
wiley   +1 more source

ACSL1‐Dependent Microglial Lipoimmunometabolic Reprogramming Underlies Cognitive Deficits in Alcohol Use Disorder

open access: yesAdvanced Science, EarlyView.
This study reveals that chronic alcohol exposure selectively upregulates ACSL1 expression in prefrontal cortical microglia, driving lipid metabolism reprogramming and lipid droplet accumulation, which activates the NLRP3 inflammasome and sustains neuroinflammation. To reverse this process, a dual‐targeted lipid nanoparticle, siACSL1@LNP‐MR, is designed
Liang Hao   +8 more
wiley   +1 more source

Aufbruchstimmung in der Rechtsmedizin?: Virtopsy Basic Course [PDF]

open access: yes, 2018
Forensic medicine aims for the documentation of medical and other forensic findings in living and deceased persons for the police and the judiciary system.
Oesterhelweg, L.
core  

DIGITAL FORENSIC IMAGING

open access: yes, 2022
DATA IMAGING LENS ...
openaire   +1 more source

Inactivation Rap2a in Endothelial Cell Prevents Pulmonary Fibrosis by Regulating Immune Microenvironment Through MAP4K4‐VCAM1 Signaling

open access: yesAdvanced Science, EarlyView.
We identified the endothelial RAP2A as a regulator of inflammatory endothelial activation in experimental lung fibrosis and suggest that targeting RAP2A‐mediated signaling may represent a potential strategy to modulate endothelial–immune crosstalk during fibrotic lung injury.
Xiaolan Zheng   +13 more
wiley   +1 more source

VIRTual autOPSY—applying CT and MRI for modern forensic death investigations

open access: yesFrontiers in Radiology
Virtual autopsy, an advanced forensic technique, utilizes cutting-edge imaging technologies such as computed tomography (CT) and magnetic resonance imaging (MRI) to investigate the cause and manner of death without the need for physical dissection.
Dominic Gascho
doaj   +1 more source

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