Results 121 to 130 of about 27,074 (259)

Recent Advances (2023–2025) of Capillary Electrophoresis‐Mass Spectrometry (CE‐MS) for Top‐Down Proteomics

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Top‐down proteomics (TDP) characterizes proteoforms in cells, tissues, and biofluids, in discovery mode and on a global scale, requiring analytical tools with high peak capacity for proteoform separation and high sensitivity for proteoform detection, given the extremely high proteoform complexity and wide proteoform concentration dynamic range.
Guijie Zhu, David A. Alvarez Rodriguez, Noah Gould, Alexander R. Ivanov, Kevin Jooß, Liangliang Sun   +5 more
wiley   +1 more source

Analysis of Carbohydrates and Glycoconjugates by Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry: An Update for 2023–2024

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley   +1 more source

Recent Advances in Top‐Down Proteomics for Single‐Cell Research

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Individual cells have distinctive molecular characteristics, including biologically relevant proteoforms. Although single‐cell (SC) molecular omics offer unprecedented insights into cellular heterogeneity and function, the characterization of proteoforms in SCs remains an uncharted territory.
Jake A. Melby, Pei Su, Fabio P. Gomes
wiley   +1 more source

BIOPHYSICAL METHODS IN FORENSIC MEDICAL EXAMINATION

Современные проблемы науки и образования (Modern Problems of Science and Education)
E.N. Gubaydullina, G.R. Mustafina, A.A. Khalikov   +2 more
openaire   +1 more source

Mass Spectrometry‐Based Extracellular Vesicle Proteomics for Biomarker Discovery

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Extracellular vesicle (EV) proteomics has emerged as a powerful platform for decoding intercellular communication and advancing biomarker discovery across human diseases. EVs carry proteins that reflect their cells of origin, offering a minimally invasive window into physiological and pathological processes.
Ya‐Juan Liu, Juan Peng, Chao Kang
wiley   +1 more source

Signed in bone: Toolmark identification of a machete and multidisciplinary 3D reconstruction in a homicide investigation. [PDF]

Forensic Sci Int Synerg
Kirbach M, Holzer A, Frey L, Tegou A, Helmrich S, Rothschild MA, Weber M.   +6 more
europepmc   +1 more source

Proteoforms in Disease: Biomedical Applications of Top‐Down Proteomics

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The proteome is a dynamic landscape of proteoforms arising from genetic mutations, alternative splicing, and post‐translational modifications (PTMs), which collectively drive biological function and disease phenotypes. Mass spectrometry (MS)‐based proteomics has emerged as an essential technique for elucidating this molecular complexity ...
Holden T. Rogers, Zachery R. Gregorich, Megan S. Gant, Zhan Gao, Julia Chamot‐Rooke, Ying Ge   +5 more
wiley   +1 more source

Whole Body Phase Angle as a Promising Marker of Disease Severity in Facioscapulohumeral Muscular Dystrophy

Muscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims To investigate its potential role as a marker of disease severity in facioscapulohumeral dystrophy (FSHD), this study examined the association between whole‐body phase angle (PhA) and clinically assessed severity in FSHD patients.
Oscar Crisafulli, Renato Baptista, Andi Nuredini, Matteo Fortunati, Luca Grattarola, Rossella Tupler, Anna Odone, Giuseppe D'Antona   +7 more
wiley   +1 more source

Cumulative Physiological Affect: Thematic Analysis of Forensic Psychological Examination Data from a Homicide Case. [PDF]

J Pers Oriented Res
Kudaibergenova A, Safuanov F, Urisbayeva A, Duisenbekov D, Kalymbetova E.   +4 more
europepmc   +1 more source

Morphological Similarity Between Edo‐Period Wooden Dentures and Maxillae in Japan: A Three‐Dimensional Analysis Using Homologous Modeling

International Journal of Osteoarchaeology, EarlyView.
ABSTRACT Wooden dentures represent a distinctive form of dental technology uniquely developed in Japan that is no longer in clinical use. Although Edo‐period (1603–1867) wooden dentures are presumed to have achieved sufficient precision, their morphological fit has not been quantitatively evaluated.
Kie Yoshida, Yuka Hatano, Moe Kosaka, Toshihiko Suzuki   +3 more
wiley   +1 more source