Results 131 to 140 of about 122,661 (263)

Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research

open access: yesMass Spectrometry Reviews, EarlyView.
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik   +3 more
wiley   +1 more source

Ion Activation Methods for Top‐Down Proteomics

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT Mass spectrometry (MS) has emerged as a premier method used to characterize the sequences of proteins. Top‐down proteomics aims to capture the multiple sources of structural diversity reflected in proteins, such as those that arise from alternative RNA splicing events or the addition of post‐translational modifications. Tandem MS (i.e., MS/MS)
Jada N. Walker, Jennifer S. Brodbelt
wiley   +1 more source

Trans Women in Incarceration: Housing, Healthcare, and Humanity [PDF]

open access: yes, 2018
This paper seeks to analyze the experience of male-to-female transgender inmates housed in men’s prisons and to propose housing and healthcare policies with humanity and safety for all in mind.
Bielous, Stanislaw
core   +1 more source

Reliability of Species Assessment of Archaeological Cremated Bone Fragments: Confidence in Diagnosis and Interobserver Agreement

open access: yesInternational Journal of Osteoarchaeology, EarlyView.
ABSTRACT The ancient practice of cremation has been documented across numerous cultures, yet burnt remains can indeed become a huge challenge for anthropologists, both in archaeological and in forensic contexts. The analysis of such skeletal material presents significant challenges associated with the alterations caused by the process of burning.
Carlotta Sala   +6 more
wiley   +1 more source

Medical-forensic research of injuries on the skulls discovered during archaeological excavations on Bolgar fortified settlement

open access: yesПоволжская археология, 2015
The article presents some preliminary results of medical and forensic analysis of traumatic injuries on the skulls from medieval burials found on the territory of Bolgar fortified settlement.
Albert I. Zholobov   +2 more
doaj  

Clinicopathological characteristics of patients with inoperable non‐small cell lung cancer harboring circulating NRF2 pathway mutations

open access: yesThe Journal of Pathology, EarlyView.
Abstract Lung cancer is the leading cause of global cancer‐related morbidity and mortality, with tobacco smoking as its strongest risk factor. Nuclear factor erythroid 2‐related factor 2 (NRF2) is a redox‐regulated transcription factor frequently dysregulated in non‐small cell lung cancer (NSCLC), leading to aggressive disease and resistance to therapy.
Jouni Härkönen   +14 more
wiley   +1 more source

The future of forensic bioinformation [PDF]

open access: yes, 2010
The collection and use of bioinformation is an important feature of contemporary efforts to ensure public safety and maintain (inter)national security.
McCartney, Carole   +2 more
core  

Hypertrophic Cardiomyopathy as a Key Feature of MRAS‐Related Noonan Syndrome: New Case and Comprehensive Literature Review

open access: yesPrenatal Diagnosis, EarlyView.
ABSTRACT Noonan syndrome (NS) is a rare multisystemic condition among the RASopathy group, characterized by a broad phenotypic spectrum and genetic variability. It results from pathogenic variants in genes regulating the RAS/MAPK pathway, affecting cell proliferation and differentiation.
Romain Martineau   +10 more
wiley   +1 more source

Audio‐guided exercise at home: Preliminary findings from a pilot study on physical activity for people with low vision

open access: yesPM&R, EarlyView.
Abstract Background: Individuals with severe visual impairments frequently refrain from regular physical activity due to multiple barriers, including transportation difficulties, financial constraints, and limited availability of exercise programs tailored to their needs. These factors often contribute to a gradual decline in mobility and independence.
Luca Correale   +7 more
wiley   +1 more source

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