Results 211 to 220 of about 85,948 (287)

Associations between TMEM106B C‐terminal fragment aggregation, age, and TDP‐43 or tau pathology

Brain Pathology, EarlyView.
TMEM106B C‐terminal fragment (CTF) aggregation represents an age‐associated, common, diffuse phenomenon emerging after midlife with a weak association with TDP‐43 or tau pathology. These findings suggest that TMEM106B fibrillization may define a distinct axis of protein aggregation in the aging human brain. Abstract Transmembrane protein 106B (TMEM106B)
Albert Acewicz, Sylwia Tarka, Michał Grzegorczyk, Radosław Rzepliński, Teresa Wierzba‐Bobrowicz, Tomasz Stępień   +5 more
wiley   +1 more source

Dual pharmacological targeting of coactivator‐associated arginine methyltransferase 1 (CARM1) and salt inducible kinase (SIK) drives ketogenesis in both hepatocytes and mice

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Ketone bodies are liver‐derived circulating energy metabolites that positively impact most hallmarks of ageing. Ketone bodies increase during calorie restriction and fasting, two of the more widely perceived methods to increase health span.
Tábata Bergonci, Troels Kjær Rosenbæk, Samuel J. Windross, Ulrik B. Keiding, Estéfano Pinilla, Katrine P. Stuckert, Jakob Hansen, Camilla B. Nielsen, Jemila Peter Gomes, Lucy R. Davies, Johan Palmfeldt, Volker Loeschcke, Charlotte U. Andersen, Ulf Simonsen, Thomas B. Poulsen, Mogens Johannsen   +15 more
wiley   +1 more source

Diagnostic Methods in Forensic Pathology: Autoptic Findings and Immunohistochemical Study in Cases of Sudden Death Due to a Colloid Cyst of the Third Ventricle. [PDF]

Diagnostics (Basel)
Montana A, Busardò FP, Tossetta G, Goteri G, Castaldo P, Basile G, Bambagiotti G.   +6 more
europepmc   +1 more source

Development and analytical validation of a targeted short‐read next generation sequencing‐based pharmacogenetic panel for comprehensive variant detection

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Genomic profiling of patients for genetic variants that modify the effect of specific medications has many benefits, including the possibility of avoiding toxicities and ensuring an adequate effect of the medication. Our intention was to develop a comprehensive, high‐quality pharmacogenetic test panel for clinical use ...
Anna Gréen, Nils Johan Fredriksson, Michael Andresen, Jon Jonasson, Malin Lindqvist Appell, Henrik Gréen   +5 more
wiley   +1 more source

Diagnosis of Drowning and the Value of the Diatom Test in Veterinary Forensic Pathology. [PDF]

Front Vet Sci, 2019
Piegari G, De Biase D, d'Aquino I, Prisco F, Fico R, Ilsami R, Pozzato N, Genovese A, Paciello O.   +8 more
europepmc   +1 more source

Accountability and Hyperaccountability in Child Protection Scandals

Child &Family Social Work, EarlyView.
ABSTRACT The number of child abuse–related deaths has decreased significantly in the United Kingdom over the past 50 years, but there remains public and political concern about the actual and perceived risk of child deaths, with resultant processes enacted to supervise child protection practice.
Robin Sen, John Devaney
wiley   +1 more source

The Forensic Pathology of Liver Trauma. [PDF]

Acad Forensic Pathol, 2018
Rogers CB, Devera R.
europepmc   +1 more source

Biological conservation at risk in Slovakia: Brown bears under attack of autocratic pressures

Conservation Science and Practice, EarlyView.
Recent governance changes in Slovakia have allowed extensive brown bear removals while reducing expert involvement. These developments raise concerns about long‐term management and consistency with EU conservation standards. The case underscores how political context affects conservation outcomes.
Michal Haring, Dusan Janak, Martin Kovanic, Ivo Pavlik   +3 more
wiley   +1 more source

Cytopathology Terminology Systems: European Federation of Cytological Societies Survey on Practice in Europe

Cytopathology, EarlyView.
Cytology terminologies are widely accepted within Europe based on EFCS survey. The Bethesda System for reporting cervical cytology and the Bethesda System for reporting thyroid cytopathology have been implemented by most of the responding countries. ABSTRACT Cytopathologists communicate with clinicians via cytopathology reports.
Ivana Kholová, Colleen Vrbin, Esther Diana Rossi, David Poller, Pinar Firat, Sevgen Onder, Beatrix Cochand‐Priollet, Henrik Griesser, Guido Fadda, Marianne Engels, Massimo Bongiovanni, Pio Zeppa, Ashish Chandra, Ambrogio Fassina, Philippe Vielh, Danijela Vrdoljak‐Mozetic, European Federation of Cytological Societies National Representatives, Shaira Sahebali, Pawel Gajdzis, Christina Kåbjörn Gustafsson, Monique Courtade‐Saidi, Maria Nasioutziki, Filipa Moreno, Robby Kibbelaar, Jaroslava Dušková, Wolfgang Pokieser, Margareta Strojan Fležar, Maria D. Lozano, Oksana Sulaieva, Pavlina Botsiun, Laszlo Vass, Ljube Ivkovski, Tibor Mezei, Nina Juric, Mikk Abram, Cornelia Amalinei, Milana Panjkovic, Dalius Baltusnikas, Aleksandrina Vlahova, Rene Gerhard, Cioly Rivero‐Colmenarez, Ljiljana Vučković, Fatlinda Sadiku, Giovanni Negri, Erion Sukaj, Jurate Asmundsson, Lucia Krivošíková   +46 more
wiley   +1 more source

Workshop on manpower development and training in toxicology and chemical safety. Luxembourg, 28 November - 2 December 1983. Industrial health and safety. EUR 9619 EN [PDF]

, 1984
Berlin, A., Smith, E., Tarkowski, S.
core