Results 31 to 40 of about 85,948 (287)

Pulmonary fat embolism: a potentially new fatal complication of SARS-CoV-2 infection. A case report

open access: yesBMC Infectious Diseases, 2023
Background So far, there have been more than 761 million confirmed cases of SARS-CoV-2 worldwide, with more than 6.8 million deaths. The most common direct causes of death for COVID-19 are diffuse alveolar injury and acute respiratory distress syndrome ...
Jiangwei Kong   +6 more
doaj   +1 more source

The meaning of different forms of structural myocardial injury, immune response and timing of infarct necrosis and cardiac repair [PDF]

open access: yes, 2015
Although a decline in the all-cause and cardiac mortality rates following myocardial infarction (MI) during the past 3 decades has been reported, MI is a major cause of death and disability worldwide.
Bello, S   +5 more
core   +1 more source

Explaining and trusting expert evidence: What is a ‘sufficiently reliable scientific basis’? [PDF]

open access: yes, 2020
Through a series of judicial decisions and Practice Directions, the English courts have developed a rule that expert evidence must have ‘a sufficiently reliable scientific basis to be admitted’.
Ward, Tony
core   +2 more sources

Neuroprotection of NRF2 against Ferroptosis after Traumatic Brain Injury in Mice

open access: yesAntioxidants, 2023
Ferroptosis and iron-related redox imbalance aggravate traumatic brain injury (TBI) outcomes. NRF2 is the predominant transcription factor regulating oxidative stress and neuroinflammation in TBI, but its role in iron-induced post-TBI damage is unclear ...
Hao Cheng   +10 more
doaj   +1 more source

Influence and challenge of COVID-19 in forensic identification

open access: yesJournal of Forensic Science and Medicine, 2020
During the COVID-19 epidemic, the professionals in the field of forensic pathology, forensic sciences in general, and clinical forensic medicine have been performing medicolegal investigation in their communities. The forensic medical personnel who carry
Bin Cong, Xin Liu
doaj   +1 more source

Confocal laser scanning microscope, raman microscopy and western blotting to evaluate inflammatory response after myocardial infarction [PDF]

open access: yes, 2015
Cardiac muscle necrosis is associated with inflammatory cascade that clears the infarct from dead cells and matrix debris, and then replaces the damaged tissue with scar, through three overlapping phases: the inflammatory phase, the proliferative phase
Cantatore, S   +6 more
core   +1 more source

A pilot study examining garment severance damage caused by a trained sharp-weapon user [PDF]

open access: yes, 2016
The pilot study summarized in this paper aimed to raise awareness of a gap that exists in the forensic textile science literature about damage caused to clothing by trained sharp-weapon users.
Carr, D. J.   +4 more
core   +1 more source

PRMT1‐Mediated LDHA Methylation Drives STAT3 Lactylation to Orchestrate Intestinal Inflammation and Tumorigenesis

open access: yesAdvanced Science, EarlyView.
This study identifies an immunometabolic axis wherein SAM‐driven PRMT1 methylates LDHA, enhancing its activity. The resultant lactate induces STAT3 K709 lactylation, which stabilizes an active conformation to promote STAT3 phosphorylation and IL‐10 expression.
Hui Wang   +12 more
wiley   +1 more source

Advance of Forensic Research in Insulin Poisoning [PDF]

open access: yesFayixue Zazhi, 2017
Insulin as a common clinical hypoglycemic agent can effectively control serves to lower the concentration of blood glucose. However, insulin overdose can lead to death.
TONG FANG, LIANG YUE, SHI QING, ET AL.
doaj   +1 more source

EEPD1 Inhibition Unleashes Antitumor Immunity in Colorectal Cancer by Activating the cGAS‐STING Pathway

open access: yesAdvanced Science, EarlyView.
In colorectal cancer, high expression of the DNA repair protein EEPD1 correlates with immune exclusion and poor prognosis. This study demonstrates that EEPD1 depletion induces genomic instability, leading to cytosolic DNA accumulation and subsequent activation of the cGAS‐STING‐type I interferon pathway. This cascade remodels the tumor microenvironment
Liyun Huo   +8 more
wiley   +1 more source

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