Results 281 to 290 of about 4,081,512 (346)

Screening and Quantification of the Synthetic Cannabinoid Receptor Agonist 5F‐MDMB‐PINACA From Seized Prison Paper Using Ultraperformance Liquid Chromatography–Mass Spectrometry Approaches

open access: yesDrug Testing and Analysis, EarlyView.
Synthetic cannabinoid receptor agonists are being infused on paper and illicitly introduced into prisons through mail correspondence. An approach to quantify and map the synthetic cannabinoid 5F‐ADB on a seized paper sample from a UK prison was determined using ultraperformance liquid chromatography–quadrupole Dalton–mass spectrometry.
Giorgia Vaccaro   +4 more
wiley   +1 more source

Identification of Three Novel Tetrahydrocannabinol Analogs in the European Market

open access: yesDrug Testing and Analysis, EarlyView.
The major isolated ingredient of “CB9” was identified as [2‐(E)‐propen‐1‐yl]‐Δ8‐tetrahydrocannabinol‐acetate of “tresconol” as [2‐propen‐2‐yl]‐Δ9‐tetrahydrocannabinol and of “CBx” as [2‐propen‐2‐yl]‐Δ8‐tetrahydrocannabinol. These compounds have no available spectroscopic or chromatographic data and have never been identified in Cannabis plants, and ...
Evangelos Dadiotis   +4 more
wiley   +1 more source

Anti‐Doping Testing at FIFA World Cup 2022

open access: yesDrug Testing and Analysis, EarlyView.
The FIFA 2022 World Cup was fully accomplished by the Anti‐Doping Lab Qatar. The article describes the doping analysis work, achievements, and lab structure in details. ABSTRACT The 22nd FIFA World Cup, the world championship for national football teams, was held in Qatar from November 20th to December 18th, 2022.
Alanod D. AlQahtani   +12 more
wiley   +1 more source

Quantitative Investigation of Nitrosamine Drug Substance‐Related Impurities (NDSRIs) Under Artificial Gastric Conditions by Liquid Chromatography–Tandem Mass Spectrometry and Structure–Activity Relationship Analysis

open access: yesDrug Testing and Analysis, EarlyView.
The study provides information about the impact of physiological gastric conditions on the unbeneficial occurrence of nitrosamine drug substance–related impurities (NDSRIs). Both main factors for nitrosation in the form of acidic conditions and the presence of nitrite were adequately chosen for triggering the conversion of drug compounds into NDSRIs ...
Matthias Vogel   +5 more
wiley   +1 more source

Effects of Dimenhydrinate on Motor Behavior and Vascular Function: Possible Implications for the Field of Sports

open access: yesDrug Testing and Analysis, EarlyView.
Regarding cardiovascular effects, DMH decreased vascular reactivity to phenylephrine and acetylcholine. We observed that the combination of DPH and 8‐Cl‐T was identified as the responsible for increasing blood pressure and heart rate in the biological model used.
Jazmín Flores‐Monroy   +3 more
wiley   +1 more source

Biology and Management of Male‐Bodied Athletes in Elite Female Sports

open access: yesDrug Testing and Analysis, EarlyView.
Graphical representation of the relationships of transgender and XY DSDF as male‐bodied athletes along the binary dimensions of biological sex. ABSTRACT The physical advantages in elite power sports that allow men to surpass women are derived from the experience of male puberty.
David J. Handelsman, Stéphane Bermon
wiley   +1 more source

Effects of the Dietary Supplement 5α‐Hydroxy‐Laxogenin in the Orchiectomized Rat Model

open access: yesDrug Testing and Analysis, EarlyView.
The dietary supplement ingredient 5α‐hydroxy‐laxogenin was investigated in the castrated male rat for potential androgenic and anabolic effects. Moreover, androgen receptor binding of 5α‐hydroxy‐laxogenin was modelled by in silico docking. While molecular modelling supports androgen receptor binding, we observed neither androgenic nor anabolic effects ...
Daniel Derwand   +4 more
wiley   +1 more source

Characterising a New Cannabis Trend: Extensive Analysis of Semi‐Synthetic Cannabinoid‐Containing Seizures From Germany

open access: yesDrug Testing and Analysis, EarlyView.
A LC–MS/MS method has been validated for analysis of semi‐synthetic cannabinoids (SSC) and selected phytocannabinoids in seizures. Further SSC‐derivatives were implemented into the method for qualitative detection. The methodology was applied to a sample collective (n = 80) including cannabis flowers, resins, edibles and vape liquids.
Marica Hundertmark   +4 more
wiley   +1 more source

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