Results 151 to 160 of about 55,409 (303)

Rapid Identification of New Psychoactive Substances in Letters by LA‐APCI‐MS

open access: yesDrug Testing and Analysis, EarlyView.
Laser ablation coupled to molecular mass spectrometry utilizing a modified atmospheric pressure chemical ionization source was used for the detection of synthetic cannabinoid receptor agonists in infused prison mail samples. ABSTRACT New psychoactive substances (NPS), especially synthetic cannabinoid receptor agonists (SCRA), are increasingly smuggled ...
Mark Wesner   +4 more
wiley   +1 more source

Bridging the Regulatory Chasm in Investigator‐Initiated Human Subject Cannabis Research

open access: yes
Clinical Pharmacology &Therapeutics, EarlyView.
Heather M. Barkholtz, William Naviaux
wiley   +1 more source

Further Insights Into the Metabolism of LGD‐4033 in Human Urine. Part 2. A New Minor Metabolite With Antagonistic Activity on the Androgen Receptor Can Indicate Recent Substance Intake

open access: yesDrug Testing and Analysis, EarlyView.
A novel early excreted minor metabolite of LGD‐4033 was detected and coded as M8. Its presence was evaluated as an indicator of recent substance intake versus end‐tail findings. Additionally, the agonist/antagonist properties of M8 and other selected LGD‐4033 metabolites on the androgen receptor (AR) were studied using in silico molecular docking and ...
Yiannis S. Angelis   +10 more
wiley   +1 more source

Simulation of the Metabolism of New Psychoactive Substances Using Electrochemistry‐Mass Spectrometry: Introducing an Innovative Software Tool for Rapid Data Evaluation

open access: yesDrug Testing and Analysis, EarlyView.
A novel software tool for the rapid and efficient simulation of the metabolism of new psychoactive substances was developed and applied to mimic the metabolism of the synthetic cannabinoid receptor agonist MDMB‐4en‐PINACA. ABSTRACT An innovative software tool for the rapid and efficient simulation of the metabolism of new psychoactive substances (NPS ...
Mark Wesner   +3 more
wiley   +1 more source

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