Results 71 to 80 of about 19,686 (268)

The neuroprotective mechanism of lithium after ischaemic stroke

Communications Biology, 2022
Using the MCAO stroke mouse model, Chen et al. identify pathways that underlie the neuroprotective properties of lithium by using inhibitors of AKT/GSK3β/β-catenin and AKT/FoxO3a/β-catenin signaling. They report that the inhibitors reverse the protective
Beina Chen, Manman Zhang, Ming Ji, Dianjun Zhang, Binjie Chen, Wenliang Gong, Xinyu Li, Yuefei Zhou, Chengyi Dong, Gehua Wen, Xiaoni Zhan, Xiafang Wu, Huiya Yuan, Enyu Xu, Maosheng Xia, Alexei Verkhratsky, Baoman Li   +16 more
doaj   +1 more source

GC in Forensic Toxicology

, 2014
Teske J, Albrecht U-V. GC in Forensic Toxicology. In: Dettmer-Wilde K, Engewald W, eds. Practical Gas Chromatography: A Comprehensive Reference. Berlin, Heidelberg: Springer; 2014: 767-782.This chapter describes the importance and the use of gas ...
Teske, Jörg, Albrecht, Urs-Vito ; https://orcid.org/, Engewald, Werner, Dettmer-Wilde, Katja   +3 more
core   +1 more source

Segmental Hair Analysis of Diphenhydramine and Cyclizine Following a Single Dose

Drug Testing and Analysis, EarlyView.
A single oral dose of diphenhydramine and cyclizine can be quantified in human head hair for a minimum of 5 months and, in certain cases, for up to 1 year following intake. Among 12 study participants, the measured concentrations ranged from 0 to 610 pg/mg within 1 year post‐intake.
Jan Bílek, Marie Katrine Klose Nielsen, Robert Kronstrand, Sys Stybe Johansen   +3 more
wiley   +1 more source

Research Status of Caenorhabditis elegans Model in Toxicology and Its Applications in Forensic Science

Fayixue Zazhi
Caenorhabditis elegans, as an emerging model organism, has been widely used in multiple disciplines such as medicine, life science, and environmental science in recent years, due to its characteristics of short life cycle, clear genetic background ...
LI Zhuo, ZENG Yi-ru, SHU Zhi-long, SUN Xue-hong, ZHANG Kui   +4 more
doaj   +1 more source

Determination of THC and THC‐COOH in Dried Capillary Blood Spots and Comparison to Venous Blood of Recreational Cannabis Consumers in a Pilot Study

Drug Testing and Analysis, EarlyView.
A new extraction method was developed and validated for the extraction of THC and THC‐COOH from capillary blood samples collected as dried blood spots. The extracts were analysed using HPLC–MS/MS resulting in high extraction efficiencies for both THC and THC‐COOH.
Matthias Bantle, Willi Schirmer, Joel Bruegger, Thomas Wüthrich, Andreas Längin, Lena Zwicker, Reto Auer, Wolfgang Weinmann   +7 more
wiley   +1 more source

The United Kingdom and Ireland Association of Forensic Toxicologists: forensic toxicology laboratory guidelines (2010)

, 2010
The UK and Ireland Association of Forensic Toxicologists (UKIAFT) consists of representatives from each of the main laboratories in the United Kingdom and Ireland offering Forensic Toxicology Services.
Cooper, G., Paterson, S., Osselton, M., Sue Paterson, M. David Osselton, Gail A.A. Cooper   +5 more
core   +1 more source

Assessment of Abuse Potential‐Related Effects of Oral Dried Kratom Leaf Powder in Healthy Normal Participants Following Single and Multiple Daily Doses

Drug Testing and Analysis, EarlyView.
In a randomized, double‐blind, placebo‐controlled study of oral dried kratom leaf powder in healthy kratom‐naive adults, no participants met the clinically meaningful opioid withdrawal threshold; abuse‐related treatment‐emergent adverse events occurred more frequently at higher doses but were generally mild and resolved without sequelae; and no serious
Marion Coe, Marilyn Huestis, Daniel Wang, Thomas Hudzik, John Bothmer, Jack Henningfield   +5 more
wiley   +1 more source

Forensic field guide

, 2022
The purpose of this document is to give information to our customers within the criminal justice system regarding services provided by the Oregon State Police Forensic Services Division (OSP FSD) and recommended methods for collecting and preserving ...

core  

Comparison of Dried Blood Spot Sampling Methods for RNA‐Based Biomarker Measurement in Anti‐Doping

Drug Testing and Analysis, EarlyView.
This study demonstrates that RNA‐based biomarkers of erythropoiesis, ALAS2 and CA1, can be reliably quantified across commonly used DBS sampling matrices, including venous and capillary blood spotted on cellulose cards and the Tasso‐M20 device. ABSTRACT Dried blood spot (DBS) sampling offers logistical advantages, but it remains unexplored whether ...
Jacob Bejder, Corentin Schlechten, Claudia Mumenthaler, Olivier Salamin, Tiia Kuuranne, Thomas Christian Bonne, Jonathan Graae, Henrik Sørensen, Nikolai B. Nordsborg, Nicolas Leuenberger   +9 more
wiley   +1 more source

Forensic toxicology [PDF]

Analytical and Bioanalytical Chemistry, 2013
C. Kostakis, P. Harpas, P. Stockham
openaire   +3 more sources