Results 161 to 170 of about 70,093 (314)

Diffusion‐Based Generative Model With Scaffold‐Hopping Strategy Yields Highly Potent Bioactive Molecules

Advanced Science, EarlyView.
SMarT‐Diff introduces a multi‐objective generative paradigm that integrates scaffold hopping with structure‐aware scoring to enable controlled exploration beyond the training distribution. The framework consistently balances drug‐likeness, synthesizes accessibility and bioactivity, yielding chemically diverse candidates with enhanced properties.
Yuwei Yang, Xiaoqing Gong, Shukai Gu, Jing Li, Bo Liu, Yanan Tian, Qianqian Zhang, Xiaojun Yao, Huanxiang Liu   +8 more
wiley   +1 more source

An Improved LandTrendr Algorithm for Forest Disturbance Detection Using Optimized Temporal Trajectories of the Spectrum: A Case Study in Yunnan Province, China

Forest disturbance mapping plays an important role in furthering our understanding of forest dynamics. The Landsat-based detection of Trends in Disturbance and Recovery (LandTrendr) algorithm is widely used in forest disturbance mapping.
Liang Hong, A-Xing Zhu, Li He
core   +1 more source

Tailoring Multifunctional Carbon Dots via Precursor Stoichiometry: Switching Between Solid‐State Fluorescence and Broadband Absorption Through Aggregation Control

Advanced Science, EarlyView.
Precursor stoichiometry programs the surface chemistry of carbon dots, directing their self‐assembly into distinct aggregation modes. Aldehyde‐enriched surfaces form ordered, hydrogen‐bonded assemblies that enable bright red solid‐state fluorescence, whereas amine‐rich surfaces promote compact π–π stacked aggregates with broadband visible‐light ...
Gaixia Yang, Hao Sun, Defa Hou, Fulin Yang, Yuan Zou, Bei Zhou, Lanxiang Liu, Xu Lin, Guanben Du   +8 more
wiley   +1 more source

A Programmable Multi‑Modal Information Encryption System Based on the Dynamic Wetting Behavior of Liquid Metal

Advanced Science, EarlyView.
This work presents a programmable multimodal information encryption device that harnesses the dynamic wetting behavior of liquid metal to achieve secure, reconfigurable, and high‐precision encryption and decryption of diverse data types, including text and images.
Xuedong Qiang, Min Mao, Yihao Wang, Nan Li, Mengyu Jiang, Chenkun Sun, Bangdeng Du, Jifei Ye, Linyan Wang, Fei Zhan, Lei Wang   +10 more
wiley   +1 more source

Topology‐Aware Deep Learning on Higher‐Order Structures for Drug Response Prediction

Advanced Science, EarlyView.
We present TopDr, a topology‐aware deep learning framework that encodes both drugs and cell lines as multiscale simplicial complexes, capturing interactions at the 0‐, 1‐, and 2‐simplex levels. By jointly integrating local higher‐order neighborhoods and global topological structures, TopDr generates enriched representations for sensitivity prediction ...
Cong Shen, Guancen Lin, Chuan‐Shen Hu, Yong Wang   +3 more
wiley   +1 more source

Full‐Stack Architectures for Intelligent Brain‐Computer Interfaces

Advanced Science, EarlyView.
System‐level overview of brain–computer interfaces (BCIs), illustrating the integration of neural signal acquisition, wireless transmission, and adaptive decoding. Advanced electrode, tissue interfaces, energy‐efficient communication, and robust algorithms collectively enable stable signal quality, real‐time processing, and closed‐loop operation ...
Hee Kyu Lee, Hyun Bin Kim, Sang Uk Park, Janghoon Joo, Jinhong Min, Geumbee Lee, Joohoon Kang, Hyoyoung Jeong, Jae‐Young Yoo, Sang Min Won   +9 more
wiley   +1 more source

New development and application needs for Earth system modeling of fire–climate–ecosystem interactions

Environmental Research Letters, 2018
Yongqiang Liu
doaj   +1 more source

Extra Climate Benefits From Afforestation Due to Reduced Forest Fragmentation in China

Advanced Science, EarlyView.
Afforestation in China reduced forest fragmentation in 2015, transforming 51.8 M ha of edge forests into interior forests. This enhanced carbon sequestration (1.4±0.2 Pg CO2e, a cooling biogeochemical effect), while reduced albedo (−0.9 Pg CO2e, a warming biophysical effect) partially offset the gain, yielding a net extra climate benefit of ...
Nan Meng, Wei Li, Philippe Ciais, Martin Brandt, Xiaowei Tong, Yanzheng Yang, Guofeng Shen, Wei Du, Lei Zhu, Yi Leng, Minxuan Sun, Mengjie Han, Xuemei Zhang, Jie Zhang, Nan Wang, Dan Tong, Chao Wu, Wenhao Dong, Shu Tao, Bo Pan   +19 more
wiley   +1 more source

Machine Learning Accelerated Non‐Adiabatic Molecular Dynamics Elucidates Local Polarization Effects on Non‐radiative Recombination in Halide Perovskites

Advanced Science, EarlyView.
This work proposes and constructs the Hefei‐NAMD‐S framework based on machine learning stacked models to investigate the relationship between local polarization and non‐radiative recombination. The results indicate that, compared with A‐site local polarization, B‐site local polarization shows a more evident association with the non‐radiative ...
Bing Yang, Xiaoli Wei, Bo Cai, Yan Yang, Xinghai Zhu, Yi Liu, Junmin Xia, Lihui Liu, Kun Cao, Wei Shen, Pengfei Xia, Shufen Chen, Siyu Chen, Jin Zhao   +13 more
wiley   +1 more source

An AI-ready remote sensing dataset for high-resolution forest disturbance mapping. [PDF]

Sci Data
Rodríguez-Paulino E, Stoffels J, Schlerf M, Röder A, Wagner A, Udelhoven T.   +5 more
europepmc   +1 more source