Results 241 to 250 of about 70,093 (314)

DNA‐Induced Entropic Gain Triggers an Allosteric Switch for Biomolecular Condensation of Heat Shock Transcription Factor 1

Angewandte Chemie, EarlyView.
Hsf1 undergoes phase separation around target DNA, activating stress‐responsive transcription. DNA binding tunes conformational dynamics of Hsf1DBD, which propagates through large‐scale domain rearrangements involving DBD–IDR interactions to regulate phase separation. This hierarchical framework illustrates how local structural events at the side chain
Soichiro Kawagoe, Hiroyuki Kumeta, Tomohide Saio   +2 more
wiley   +2 more sources

Effective Conservation Decisions Require Models Designed for Purpose: A Case Study of Boreal Caribou in Ontario's Ring of Fire. [PDF]

Ecol Evol
Dyson ME, Endicott S, Simpkins C, Turner JW, Avery-Gomm S, Johnson CA, Leblond M, Neilson EW, Rempel R, Wiebe PA, Baltzer JL, Hughes J, Stewart FEC.   +12 more
europepmc   +1 more source

A high‐fat diet with vitamin D and propylthiouracil produces a pro‐atherogenic phenotype in rats

Animal Models and Experimental Medicine, EarlyView.
Male Sprague–Dawley rats received a cholesterol‐rich high‐fat diet supplemented with vitamin D and propylthiouracil for 11 weeks. The model induced dyslipidemia (increased total cholesterol/low‐density lipoprotein, decreased triglycerides), inflammation (increased interleukin‐6 and serum amyloid A), hypercalcemia, and reduced circulating endothelial ...
Angélique Lewies, Vitaris Kodogo, Johannes Frederik Wentzel, Francis Edwin Smit   +3 more
wiley   +1 more source

Genetic prediction of blood cell reactivity and its potential causal influence on bone continuity and density disorders

Animal Models and Experimental Medicine, EarlyView.
We applied Mendelian randomization to explore causal links between blood cell traits and skeletal disorders. Using genetic instruments from large‐scale summary statistics, we assessed effects on bone continuity, density, and structural integrity. Sensitivity and reverse analyses confirmed robust associations, highlighting potential shared biological ...
Zhiqin Deng, Zhe Zhao, Wenting Jiang, Xiaoqiang Chen, Jianquan Liu, Xu Tao, Zhengyang Lin, Zhenhan Deng, Wencui Li   +8 more
wiley   +1 more source

Land Use Shapes Ant Communities: Functional and Compositional Differences Between Oak Forests and Chestnut Orchards in Mediterranean Mountain Landscapes of Northern Portugal. [PDF]

Insects
Lourenço-Lima C, Gonçalves F, Villa M.
europepmc   +1 more source

Legacies of foundation species shape life after death. [PDF]

Sci Adv
Kopecky KL, Castorani MCN, Tuff T, Barker Plotkin A, Bell DM, Johnstone JF, Kominoski JS, Nippert JB, Nytch CJ, Pennings SC, Reed DC, Shiels AB, Suding KN.   +12 more
europepmc   +1 more source

Long-Term Grazing Exclusion Reveals Taxonomic and Functional Reorganization of Plant Communities in an Insular Mediterranean Geopark. [PDF]

Plants (Basel)
Kakampoura V, Zevgolis YG, Zouros N, Panitsa M, Dimitrakopoulos PG.   +4 more
europepmc   +1 more source

Optimized Selenium‐Doped Nanocomposites for Enhanced Polymer Gel Performance in Permeability Reduction

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT Excessive water production in mature oil fields necessitates robust shut‐off treatments, yet conventional polymer gels often fail under high‐temperature and high‐salinity conditions. This study aims to enhance gel thermal stability and mechanical strength by incorporating selenium‐doped Ag/AgO–ZnO nanocomposites synthesized via a novel green ...
Fadhil F. Sead, Farag M. A. Altalbawy, M. Sudhakara Reddy, Badri Narayan Sahu, Sridharan Sundharam, Sanjeev Kumar, Atreyi Pramanik, Aseel Smerat, Fatimah Pashtun   +8 more
wiley   +1 more source

A cost‐effective DNA extraction protocol for long‐read sequencing in non‐model plants

Applications in Plant Sciences, EarlyView.
Abstract Premise Third‐generation sequencing has revolutionized genomics, enabling in‐depth analysis of genome sequence, structure, and epigenetic features. Yet, extracting high‐quality DNA for long‐read sequencing remains a bottleneck—particularly in non‐model plants, such as mature trees growing in natural environments, which often contain abundant ...
Sofia Gaischuk, Cintia F. Marchetti, Ezequiel Petrillo, Fernando A. Rabanal, Detlef Weigel, Nicolás Bellora, M. Verónica Arana   +6 more
wiley   +1 more source

A multi-source remote sensing dataset for large-scale forest monitoring. [PDF]

Data Brief
D'Amico G, Botticelli D, Marcelli G, Mattioli W, Chirici G, Vangi E, Borghi C, Corona P, Schumacher J, Breidenbach J, Su Y, Mehtätalo L, Francini S.   +12 more
europepmc   +1 more source