Results 41 to 50 of about 719,039 (308)

A Unifying Concept for Growth Trends of Trees and Forests – The “Potential Natural Forest”

Frontiers in Forests and Global Change, 2020
Changes in the environment will alter the growth rate of trees and forests. Different disciplines assess such growth rates differently, for example, with tree-ring width data, forest inventories or with carbon-flux data from eddy covariance towers.
Mario Trouillier, Marieke van der Maaten-Theunissen, Tobias Scharnweber, Martin Wilmking   +3 more
doaj   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Drought and heat reduce forest carbon uptake

Nature Communications, 2023
Climate extremes threaten the land carbon sink and it is important to understand their impact in a changing climate. A recent study provides new insights on reduced forest carbon uptake during the severe 2022 drought and heatwave across Europe.
Sebastian Wolf, Eugénie Paul-Limoges
doaj   +1 more source

Stand Dynamics and Disturbance History of Champlain Valley Clayplain Forests [PDF]

, 2017
Studies of stand dynamics can explain how species interactions and disturbances drive forest structure and recruitment patterns of tree species. It is difficult to generate an understanding of stand dynamics and successional trends of forests in areas ...
Murray, Helena F
core   +1 more source

Dynamic Integration with Random Forests [PDF]

, 2006
Random Forests (RF) are a successful ensemble prediction technique that uses majority voting or averaging as a combination function. However, it is clear that each tree in a random forest may have a different contribution in processing a certain instance.
Tsymbal, A., Pechenizkiy, M., Cunningham, P.   +2 more
openaire   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Optimized Forest-Ruth- and Suzuki-like algorithms for integration of motion in many-body systems

, 2001
An approach is proposed to improve the efficiency of fourth-order algorithms for numerical integration of the equations of motion in molecular dynamics simulations.
Allen, Burden, Dullweber, Forest, Frenkel, Gear, I.M. Mryglod, I.P. Omelyan, Kahan, Krech, McLachlan, Omelyan, Omelyan, Qin, R. Folk, Sofroniou, Stuart, Suzuki, Suzuki, Suzuki, Swope, Tuckerman, Yoshida   +22 more
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Wall-to-Wall Tree Type Mapping from Countrywide Airborne Remote Sensing Surveys

Remote Sensing, 2017
Although wall-to-wall, accurate, and up-to-date forest composition maps at the stand level are a fundamental input for many applications, ranging from global environmental issues to local forest management planning, countrywide mapping approaches on the ...
Lars T. Waser, Christian Ginzler, Nataliia Rehush   +2 more
doaj   +1 more source