Results 71 to 80 of about 4,776,147 (349)

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu, Yinjiao Fei, Jiaxuan Ding, Kexin Shi, Jinyan Luo, Yuchen Zhu, Xingjian Sun, Gefei Jiang, Yuandong Cao, Weilin Xu, Shu Zhou   +10 more
wiley   +1 more source

Plasticity of Fine-Root Traits Under Long-Term Irrigation of a Water-Limited Scots Pine Forest

Frontiers in Plant Science, 2019
Trait-based approaches are increasingly used to investigate plant strategies for resource acquisition, growth, or competition between individual organisms or across species. However, the characterization of responses to environmental stimuli by fine-root
Ivano Brunner, Claude Herzog, Lucía Galiano, Lucía Galiano, Lucía Galiano, Arthur Gessler   +5 more
doaj   +1 more source

Impact of Asymptomatic Intracranial Hemorrhage on Outcome After Endovascular Stroke Treatment

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Endovascular treatment (EVT) achieves high rates of recanalization in acute large‐vessel occlusion (LVO) stroke, but functional recovery remains heterogeneous. While symptomatic intracranial hemorrhage (sICH) has been well studied, the prognostic impact of asymptomatic intracranial hemorrhage (aICH) after EVT is less certain ...
Shihai Yang, Chengsong Yue, Zhuang Li, Xiaolei Shi, Haoxuan Zhu, Jie Yang, Linyu Li, Jiaxing Song, Shitao Fan, Gaoming Li, Wenzhe Sun, Zhixian Ye, Jiacheng Huang, Dahong Yang, Jinfu Ma, Xu Xu, Zhixi Wang, Lilan Wang, Guojian Liu, Fengli Li, Changwei Guo, Li Qi, Wenjie Zi   +22 more
wiley   +1 more source

Tree‐Ring Anatomy Improves the Reliability of Temperature Reconstructions Using Relict Wood

Geophysical Research Letters
Tree rings are crucial for reconstructing past climates, with maximum latewood density (MXD) as a key metric. However, wood integrity is critical for accurate MXD‐based reconstructions, raising concerns when using potentially degraded relict wood ...
Stefan Klesse, Jesper Björklund, Marina V. Fonti, Daniel Nievergelt, Georg von Arx, Rashit M. Hantemirov, Vladimir V. Kukarskih, Lisbeth Garbrecht Thygesen, Nanna Bjerregaard Pedersen, Patrick Fonti   +9 more
doaj   +1 more source

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

Coupling growth and mortality models to detect climate drivers of tropical forest dynamics [PDF]

, 2013
Climate models for the coming century predict rainfall reduction in the Amazonian region, including deep changes in water availability for tropical rainforests.
Aubry-Kientz, Mélaine, Rossi, Vivien, Boreux, J.J., Hérault, Bruno   +3 more
core  

Forest microclimate dynamics drive plant responses to warming

Science, 2020
Local factors restrain forest warming Microclimates are key to understanding how organisms and ecosystems respond to macroclimate change, yet they are frequently neglected when studying biotic responses to global change. Zellweger et al.
Florian Zellweger, P. De Frenne, J. Lenoir, P. Vangansbeke, K. Verheyen, M. Bernhardt‐Römermann, L. Baeten, R. Hédl, I. Berki, J. Brunet, Hans Van Calster, M. Chudomelová, G. Decocq, T. Dirnböck, T. Durak, T. Heinken, B. Jaroszewicz, M. Kopecký, F. Máliš, M. Macek, M. Malicki, T. Naaf, T. Nagel, A. Ortmann‐Ajkai, P. Petřík, R. Pielech, Kamila Reczyńska, W. Schmidt, T. Standovár, Krzysztof Świerkosz, Balázs Teleki, Ondřej Vild, M. Wulf, D. Coomes   +33 more
semanticscholar   +1 more source

Development of a Personalized Visualization and Analysis Tool to Improve Clinical Care in Complex Multisystem Diseases With Application to Scleroderma

Arthritis Care &Research, EarlyView.
Objective In complex diseases, it is challenging to assess a patient's disease state, trajectory, treatment exposures, and risk of multiple outcomes simultaneously, efficiently, and at the point of care. Methods We developed an interactive patient‐level data visualization and analysis tool (VAT) that automates illustration of the trajectory of a ...
Ji Soo Kim, John Scott, Lauren Fisher, Lauren N. Smith, Willie Stewart, Adrianne Woods, Rob Smithwright, Diane Koher, Parastoo Aslanbeik, Aalok B. Shah, Brad Tibbils, Samantha I. Pitts, Ayse P. Gurses, Yushi Yang, Ana‐Maria Orbai, Antony Rosen, Laura K. Hummers, Scott L. Zeger, Ami A. Shah   +18 more
wiley   +1 more source

Changes in planned and unplanned canopy openings are linked in Europe’s forests

Nature Communications
Canopy openings are increasing in Europe’s forests, yet the contributions of anthropogenic and ecological agents of disturbance to this increase remain debated.
Rupert Seidl, Cornelius Senf
doaj   +1 more source

Scientifically based biodiversity management in timber concessions: contribution to conservation and sustainable use of biodiversity [PDF]

, 2016
During the past 25 years, forest laws in Central African countries have undergone major changes. Management plans were made mandatory: nearly 19 million hectares of timber concessions (38% of total granted concessions) were subject to a management plan ...
Bayol, Nicolas, Chevalier, Jean-François, Doumenge, Charles, Gourlet, Sylvie, Pasquier, Alexendra   +4 more
core