Results 141 to 150 of about 195,611 (300)

Sustainable Phosphorylated Cellulose Nanocrystals: A Dual‐Affinity Platform for High‐Efficiency Enrichment of Intact Glycopeptides and Phosphopeptides

open access: yesAdvanced Science, EarlyView.
AAA ABSTRACT Protein glycosylation and phosphorylation are critical post‐translational modifications (PTMs) governing nearly all cellular functions, yet their analysis remains challenging due to reliance on costly and unsustainable enrichment materials.
Jiaying Li   +9 more
wiley   +1 more source

Multi‐Omics Insights Into the Mechanisms of Early Muscle Fiber Difference and Transformation Between Lean‐Type and Chinese Indigenous Pigs

open access: yesAdvanced Science, EarlyView.
Multi‐omics analyses uncover breed‐specific cis‐regulatory landscapes and higher‐order chromatin architectural differences that underlie early postnatal muscle fiber divergence in pigs. A super‐enhancer upstream of PPP3CB recruits MEF2C to activate PPP3CB transcription, while the PPP3CB–MEF2C positive feedback loop promotes oxidative muscle fiber ...
Shuailong Zheng   +8 more
wiley   +1 more source

Accelerated forest fragmentation leads to critical increase in tropical forest edge area. [PDF]

open access: yesSci Adv, 2021
Fischer R   +6 more
europepmc   +1 more source

Erasable FAP Targeted Spray‐On Probe for Fluorescence‐Guided Surgery

open access: yesAdvanced Science, EarlyView.
We present the first erasable spray‐on probe for fluorescence‐guided surgery. Following topical delivery, FAP‐FLASH550 targets fibroblast activation protein–expressing stromal cells, delineating tumor margins with high tumor‐to‐background ratios. A 365 nm UV light pulse rapidly erases fluorescent signals through triazene photodegradation and subsequent
Zachary Rabinowitz   +2 more
wiley   +1 more source

Constraint of Lignin–Carbohydrate Complex Orchestrated on Polyphenol in Oil–Water Interface Targeting Ulcerative Colitis Therapy

open access: yesAdvanced Science, EarlyView.
This study constructed the W1/O/W2 emulsion–based targeted therapy delivery system for ulcerative colitis (UC) utilizing LCC as surfactant for the first time. This multifunctional emulsion offered certain therapeutic advantages for UC, including targeted colonic delivery of active compounds, synergistic modulation of gut microbiota through combined ...
Qian Wu   +9 more
wiley   +1 more source

Degradation in edge forests caused by forest fragmentation

open access: yesCarbon Research
Abstract Deforestation turns intact forests into fragments and creates edge forests. These edge forests experience degradation due to edge effects and may become vulnerable to climate extremes such as drought and fire. Estimating carbon dynamics in fragmented forests requires accurately mapping these edge forests, along with incorporating ...
Minxuan Sun   +8 more
openaire   +1 more source

Distribution and genetic variability of Staphylinidae across a gradient of anthropogenically influenced insular landscapes [PDF]

open access: yes, 2016
This paper describes the distribution and genetic variability of rove beetles (Coleoptera Staphylinidae) in anthropogenically influenced insular landscapes.
Borges, Paulo A. V.   +5 more
core  

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

open access: yesAdvanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li   +7 more
wiley   +1 more source

A Forest of Blue - Canada's Boreal Forest, the World's Waterkeeper [PDF]

open access: yes, 2011
Describes how the lakes, rivers, and wetlands comprising the boreal forest preserve biodiversity, mitigate global climate change effects, and offer food and cultural benefits to rural communities.

core  

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