Results 131 to 140 of about 120,573 (301)

Single‐Cell Dissection of Tumor‐Infiltrating Lymphocytes Reveals Cellular Architecture Predictive of Therapeutic Efficacy in Acral Melanoma

Advanced Science, EarlyView.
Autologous tumor‐infiltrating lymphocyte (TIL) therapy shows promising efficacy in acral melanoma, yet determinants of durable response remain unclear. By integrating single‐cell transcriptomics and TCR sequencing, this study reveals that TIL products enriched for T follicular helper and intermediate exhausted T cells establish persistent clonal ...
Chao Zhang, Wanyi Xiao, Hongru Shen, Fenge Li, Ting Li, Weihong Zhang, Haotian Liu, Ziwei Gao, Hongyu Wang, Xiubao Ren, Kexin Chen, Xiangchun Li, Jilong Yang   +12 more
wiley   +1 more source

Forest genomics research and development in Canada: Priorities for developing an economic framework [PDF]

, 2015
Ilga Porth, Gary Bull, Suborna Ahmed, Yousry A. El‐Kassaby, Mark Boyland   +4 more
openalex   +1 more source

CoalQC - Quality control while inferring demographic histories from genomic data: Application to forest tree genomes [PDF]

, 2020
Ajinkya Bharatraj Patil, Sagar Sharad Shinde, S. Raghavendra, Bhuthiah Satish, C.G. Kushalappa, Nagarjun Vijay   +5 more
openalex   +1 more source

Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy

Advanced Science, EarlyView.
Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu, Mengtao Sun, Lusheng Li, Jieqiong Wang, Shibiao Wan   +4 more
wiley   +1 more source

Genomic science provides new insights into the biology of forest trees [PDF]

, 2015
Andrew Groover
openalex   +1 more source

Forecasting Root Rot Disease through Predictive Microbial Functional Profiling

Advanced Science, EarlyView.
Predicting soil‐borne disease moves beyond observation with a framework that elevates microbial functional genes into reliable forecasting biomarkers. By coupling targeted qPCR assays for core stress‐response genes with machine learning, this method detects root rot risks in pre‐symptomatic soils with over 80% accuracy.
Chuan You, Peng Ren, Ying Guan, Kai Gong, Zhen Hua, Wuxian Zhou, Xinlan Mei, Yikui Wang, Xiaofang Wang, Yangchun Xu, Qirong Shen, Zhong Wei   +11 more
wiley   +1 more source

Pharmacogenetic GWAS meta-analysis of LDL cholesterol response to statins [PDF]

, 2014
Cardiolog
Barnes, MR, Consortium, GIST, Deshmukh, HA, Hitman, G, Jukema, JW, Krauss, RM, Postmus, I, Psaty, BM, Tardif, JC, Trompet, S   +9 more
core  

Polydopamine‐Encapsulated Probiotics Restore Gut Homeostasis and Reinstate Macrophage Efferocytosis in Systemic Lupus Erythematosus

Advanced Science, EarlyView.
Polydopamine‐encapsulated probiotics restore gut homeostasis and reinstate macrophage efferocytosis, thereby reestablishing immune tolerance and mitigating systemic autoimmunity, highlighting a bioengineered microbiota‐based therapeutic strategy for SLE.
Ruimiao Wu, Mei Liu, Changxing Gao, Cheng Zhao, Feijie Zhao, Shuqing Dong, Bo Zhang, Qianmei Liu, Wenqian Zhang, Ming Zhao, Qianjin Lu   +10 more
wiley   +1 more source

CartograTree: Enabling landscape genomics for forest trees

, 2016
Nic Herndon, Emily Grau, Iman Batra, Steven A. Demurjian, Hans Vasquez-Gross, Margaret Staton, Jill Wegrzyn   +6 more
openalex   +2 more sources

Defining a robust biological prior from Pathway Analysis to drive Network Inference [PDF]

, 2011
Inferring genetic networks from gene expression data is one of the most challenging work in the post-genomic era, partly due to the vast space of possible networks and the relatively small amount of data available. In this field, Gaussian Graphical Model
Ambroise, Christophe, Guedj, Mickael, Jeanmougin, Marine   +2 more
core   +1 more source