Results 111 to 120 of about 37,123 (317)

Tumor‐Derived LAMB3 Drives Immunosuppressive LRRC15+ Fibroblast Formation During Pancreatic Ductal Adenocarcinoma Development

Advanced Science, EarlyView.
A single‐cell atlas of pancreatic ductal adenocarcinoma development reveals progressive ductal‐fibroblast‐immune crosstalk. Tumor‐derived LAMB3 drives the formation of immunosuppressive LRRC15+ fibroblasts through the ITGB1/FAK/MAPK/FOSL2 signaling. Glycolytic reprogramming upregulates LAMB3 and correlates with LRRC15+ fibroblast enrichment.
Xuqing Shi, Hangqi Liu, Jianru Sun, Xiaoding Liu, Xinping Jv, Longyun Chen, Yuhan Zhang, Hui Zhang, Xudong Xing, Ruiyu Li, Xinyi Ke, Jun Wang, Xianglin Yin, Bohan Liu, Qixian Liu, Yuan Wang, Junliang Lu, Shiyi Liu, Junyi Pang, Yumeng Cai, Menghua Dai, Fan Bai, Huanwen Wu, Zhiyong Liang   +23 more
wiley   +1 more source

Impact of Wood Structure Variability on the Surface Roughness of Chestnut Wood

Applied Sciences
Wood constitutes a unique and valuable material that has been used from ancient times until nowadays in a wide variety of applications, in which the surface quality of wood often constitutes a critical factor.
Marina Chavenetidou, Vasiliki Kamperidou
doaj   +1 more source

Critical biomass harvesting – Applying a new concept for Swedish forest soils [PDF]

, 2018
The contribution of forest harvesting to base cation losses and soil acidification has increased in recent years in Sweden, as the demand for bioenergy has increased and the sulphur deposition has decreased.
Belyazid, Salim, Cecilia Akselsson, Akselsson, Cecilia, Salim Belyazid, Belyazid, Salim,   +4 more
core   +1 more source

Nanoscale Spatial Organization of ARC High‐ and Low‐Order Assemblies at Excitatory Synapses

Advanced Science, EarlyView.
ARC (Activity‐Regulated Cytoskeleton‐Associated protein) mediates synaptic plasticity by forming nanoscale assemblies in neurons. Using super‐resolution microscopy and time‐resolved anisotropy with targeted tagging, the study reveals low‐order ARC assemblies at synapses colocalizing with AMPARs, semi‐circular structures at endocytic zones, and 60–80 nm
Martina Damenti, Giovanna Coceano, Mariline Mendes Silva, Jonatan Alvelid, Chiara Sgattoni, Andrea Volpato, Lea Rems, Luciano A. Masullo, Eduard M. Unterauer, Rafal Kowalewski, Lucie Delemotte, Erdinc Sezgin, Ralf Jungmann, Ilaria Testa   +13 more
wiley   +1 more source

Effects of post-fire logging on forest surface air temperatures in the Siskiyou Mountains, Oregon, USA

, 2010
Following stand-replacing wildfire, post-fire (salvage) logging of fire-killed trees is a widely implemented management practice in many forest types. A common hypothesis is that removal of fire-killed trees increases surface temperatures due to loss of ...
J. G. Martin, Fontaine, J.B., J. L. Campbell, Campbell, J.L., Law, B.E., B. E. Law, Martin, J.G., Donato, D.C., J. B. Fontaine, D. C. Donato   +9 more
core   +1 more source

Recent Advances in Laser‐Induced Graphene‐Based Gas Sensors: From Sensing Mechanisms to Biomedical Applications

Advanced Science, EarlyView.
Laser‐induced graphene (LIG) provides a scalable, laser‐direct‐written route to porous graphene architecture with tunable chemistry and defect density. Through heterojunction engineering, catalytic functionalization, and intrinsic self‐heating, LIG achieves highly sensitive and selective detection of NOX, NH3, H2, and humidity, supporting next ...
Md Abu Sayeed Biswas, Ankan Dutta, Shuvendu Das, Abu Musa Abdullah, Wanqing Zhang, Fatema Tuz Zohra, Huanyu Cheng   +6 more
wiley   +1 more source

Cuproptosis and Mitophagy Mediated by the THUMPD1/IGF2R‐Dependent Suppression of AKT and Activation of AMPK Signaling Suppress Lung Adenocarcinoma Progression

Advanced Science, EarlyView.
THUMPD1 drives a tumor‐suppressive signaling cascade in lung adenocarcinoma by promoting IGF2R expression. IGF2R associates with PPP2R1A to suppress AKT and activate AMPK, leading to SLC31A1 upregulation and copper accumulation. Elevated copper disrupts mitochondrial metabolism and induces excessive mitophagy, thereby restraining tumor growth and ...
Kai Wu, Bo Qin, Zhuoyu Gu, Weizheng Ding, Xiaoming Chen, Kaishang Zhang, Yujin Qiao, Shuang Yuan, Song Zhao, Xiangnan Li, Peng Zhang   +10 more
wiley   +1 more source

OPTIMUM RATE OF FOREST HARVESTING

The Forestry Chronicle, 1966
The economic conditions that must hold good for (1) an efficient allocation of primary factors of production for harvesting forest resources and (2) allocation of these forest resources between present use and use in future have been given. The concept of user cost has been applied to specify temporal efficiency in harvesting of resources, and a ...
openaire   +1 more source

Both Forest Harvesting and Hydropower Dams Yielded Negative Impact on Low Flow Regimes in the Zagunao River Watershed, Southwest China

, 2020
Forest harvesting and hydropower dams can significantly affect flow regimes (magnitude, timing, duration, frequency, and variability), resulting in changes in degraded aquatic ecosystems and unstable water supply.
Hou, Yiping, Zhiwei Jiang, Mingfang Zhang, Jiang, Zhiwei, Zhang, Mingfang, Yiping Hou   +5 more
core   +1 more source

DNA Replication Errors Drive Genome‐Wide Small Inverted Triplication Dynamics

Advanced Science, EarlyView.
This study provides insight into the dynamic equilibrium mechanism of a novel structural variant, small inverted triplication (SIT), which is generated by misalignment of the 3’ flap generated under DNA replication stress with palindromic sequence. Alternatively, the end sequence may fold back on itself to form an inverted fragment.
Yi Lei, Yu Zhou, Haitao Sun, Hang Yuan, Xinyu Pei, Jessica D. Hess, Yao Yan, Zunsong Hu, Mian Zhou, Zhaohui Gu, Li Zheng, Xiwei Wu, Binghui Shen   +12 more
wiley   +1 more source